Comparative phytochemical and biological evaluation of Egyptian Swinglea glutinosa stems and leavesDownload PDF Download PDF ArticleOpen accessPublished: 04 June 2025Reham Hassan Mekky1 na1,Mareena M. Thabet1 na1,Omayma El-Gindi1,Mohamed Adel Said2,Safwat A. Ahmed3 &…Reda F. A. Abdelhameed3,4 Scientific Reports volume 15, Article number: 19543 (2025) Cite this articleMetrics detailsSubjectsChemical biologyComputational biology and bioinformaticsMetabolomicsAbstractThe hydroalcoholic extracts of both stems and leaves of Egyptian Swinglea glutinosa have been evaluated for their biological activities and phytochemical profiling. LC–MS/MS assists in identifying 80 phytoconstituent compounds that alternate between the stem and leaves, the majority of which are new to the genus. Biological investigation results revealed the superiority of stem extract in inhibiting α-amylase and α-glucosidase enzymes scoring IC50 (15.32 ± 0.76) and (0.656 ± 0.03) over the leaves extract, which gives IC50 (112.1 ± 5.55) and (2.721 ± 0.13) respectively at (P