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Here are today's research calls that investors need to know, as compiled by The Fly.Top 5 Upgrades:Deutsche Bank upgraded Cisco (CSCO) to Buy from Hold with a price target of $73, up from $65. The firm sees improved visibility towards "durable" mid-single-digit growth in upcoming years for Cisco, with tailwinds from artificial intelligence, a Campus portfolio refresh, more favorable near-term competitive dynamics in Networking and improved scale in Security.TD Cowen upgraded Celsius Holdings (CELH) to Buy from Hold with a price target of $55, up from $37. The firm expects to see continued improvement through the summer as Celsius' comparable sales ease from 35% in May to 19% in June and 11% in July.Stifel upgraded Incyte (INCY) to Buy from Hold with a price target of $107, up from $75. This weekend's presentation of preliminary INCA033989 dose-escalation data in essential thrombocythemia patients "represents a best-case scenario," the firm tells investors in a research note.Wells Fargo upgraded Celanese (CE) to Overweight from Equal Weight with a price target of $66, up from $45. The firm sees potential for sequential earnings improvement on cost savings and reduced maintenance and notes its outlook assumes no demand improvement near term.Wells Fargo upgraded Wix.com (WIX) to Overweight from Equal Weight with a price target of $216, up from $173. The firm says its "strong" partner channel checks leave it confident Wix can take price in fiscal 2026 and raise bookings by 2%.Top 5 Downgrades:BofA downgraded CoreWeave (CRWV) to Neutral from Buy with a price target of $185, up from $76. Noting that the stock has run up 145% following Q1 results, the firm says it believes much of the near-term upside has been priced in.H.C. Wainwright downgraded Sarepta (SRPT) to Sell from Neutral with a $10 price target. The company announced another death due to acute liver failure in a second non-ambulatory Duchenne muscular dystrophy patient treated with Elevidys, and is suspending shipments of the drug to non-ambulatory DMD patients until an immunosuppressive regimen can be agreed upon with regulators and implemented, the firm tells investors in a research note. Piper Sandler also downgraded Sarepta to Neutral from Overweight with a price target of $36, down from $70.Baird downgraded Pros Holdings (PRO) to Neutral from Outperform with a price target of $18, down from $27. The firm says that given recent internal changes at the company, it is "increasingly concerned" about Pros' ability to execute its long-term targets.Jefferies downgraded Packaging Corp. (PKG) to Hold from Buy with a price target of $205, down from $245. The firm still views Packaging Corp. as best in class, but sees the company's competitive edge flattening and the stock limited by its premium valuation.Citizens JMP downgraded Angi Inc. (ANGI) to Market Perform from Outperform without a price target following a transfer of coverage. The several strategic changes underway have the potential to improve the core fundamentals of Angi's marketplace, but competition among digital home improvement and maintenance marketplaces has intensified, the firm says.Terms and Privacy PolicyPrivacy & Cookie SettingsMore InfoS&P Futures5,991.25 +6.25 (+0.10%)Dow Futures42,248.00 +20.00 (+0.05%)Nasdaq Futures21,762.25 +31.75 (+0.15%)Russell 2000 Futures2,116.80 -2.10 (-0.10%)VIX21.60 +2.49 (+13.03%)Gold3,404.30 -2.60 (-0.08%)PortfolioSign in to access your portfolioSign inTop gainersCERO CERo Therapeutics Holdings, Inc. 19.83 +12.96 (+188.73%)PCT PureCycle Technologies, Inc. 14.12 +2.25 (+18.96%)WLY John Wiley & Sons, Inc. 40.72 +3.69 (+9.96%)CRK Comstock Resources, Inc. 28.86 +2.40 (+9.07%)JBL Jabil Inc. 196.89 +16.07 (+8.89%)Top losersENPH Enphase Energy, Inc. 34.92 -11.01 (-23.97%)FSLR First Solar, Inc. 143.90 -31.35 (-17.89%)BUR Burford Capital Limited 10.91 -1.73 (-13.69%)SGRY Surgery Partners, Inc. 20.33 -2.84 (-12.26%)PTON Peloton Interactive, Inc. 6.12 -0.81 (-11.76%)Most activeLCID Lucid Group, Inc. 2.1500 0.0000 (0.00%)NVDA NVIDIA Corporation 144.12 -0.57 (-0.39%)VALE Vale S.A. 9.35 -0.47 (-4.79%)F Ford Motor Company 10.42 -0.20 (-1.88%)TSLA Tesla, Inc. 316.35 -12.78 (-3.88%)Earnings eventsTrending tickersCERO CERo Therapeutics Holdings, Inc. 19.83 +12.96 (+188.73%)CRWV CoreWeave, Inc. 171.93 +13.43 (+8.47%)CRCL Circle Internet Group 149.15 -1.91 (-1.26%)CRWD CrowdStrike Holdings, Inc. 492.03 +12.64 (+2.64%)TSLA Tesla, Inc. 316.35 -12.78 (-3.88%)Top economic events