Support Care Cancer. 2025 Jun 26;33(7):631. doi: 10.1007/s00520-025-09690-5.ABSTRACTOBJECTIVE: This study aims to explore the effects and safety of Baduanjin on lung cancer patients post-surgery.METHODS: We conducted a comprehensive search of ten databases for relevant studies up to November 1, 2024. Studies included RCTs where Baduanjin was compared with respiratory training, routine care or no treatment. Statistical analyses and forest plots were generated using Review Manager 5.4.1. Results were expressed as mean difference with 95% confidence interval. The GRADE tool was used to assess the level of evidence for all outcomes.RESULTS: Nine RCTs involving 795 lung cancer patients who underwent lung resection surgery were included in meta-analysis. Baduanjin showed significant improvements compared to comparison group in 6-min walk distance (MD = 22.93, 95% CI [10.60, 35.26], P = 0.0003), FEV1 (MD = 0.27, 95% CI [0.11, 0.44], P = 0.001), FVC (MD = 0.34, 95% CI [0.14, 0.54], P = 0.0008), and FACT-L (MD = 20.46, 95% CI [9.48, 31.44], P = 0.0003). Additionally, Baduanjin significantly reduced the self-rating anxiety scale (MD = - 6.68, 95% CI [- 10.05, - 3.32], P = 0.0001) and self-rating depression scale scores (MD = - 6.15, 95% CI [- 7.83, - 4.46], P < 0.0001). No adverse events were reported in the included studies.CONCLUSION: Baduanjin is a safe and effective home-based feasible rehabilitation measure for enhancing postoperative activity tolerance, lung function, and quality of life while reducing negative emotions in patients after lung cancer surgery. However, due to the limitations, including low-quality evidence, high heterogeneity, and insufficient safety data in this review, the results should be interpreted cautiously. More rigorously designed, high-quality RCTs should be conducted in the future while emphasizing patient compliance and the safety of the interventions.PMID:40571840 | DOI:10.1007/s00520-025-09690-5