Country: Puerto Rico (The United States of America) Source: Centers for Disease Control and Prevention Please refer to the attached file. SummaryWhat is already known about this topic?Dengue, a mosquitoborne disease that can lead to severe illness or death, is endemic in tropical and subtropical regions worldwide. The most recent outbreak in Puerto Rico occurred in 2013.What is added by this report?During 2024, Puerto Rico reported 6,291 dengue cases and surpassed the epidemic threshold, prompting declaration of a local public health emergency. Approximately one half of patients (52.3%) were hospitalized, 264 (4.2%) had severe dengue cases, and 11 (0.2%) persons died. Persons aged 10–19 years accounted for 28.4% of severe cases.What are the implications for public health practice?Improved case recognition and clinical management facilitate improved outcomes. To reduce mosquito bite risk, residents of and visitors to Puerto Rico should consider using repellents, wearing protective clothing, and staying in places with door and window screens.