TLDR:Circle launches native USDC on Sei, replacing reliance on Noble-issued USDC.CCTP V2 enables direct USDC transfers across 13 chains with no wrapping needed.Sei’s total value locked grew 188% YTD, now surpassing $600 million in assets.New integration targets growth in gaming, DeFi, payments, and institutional use.Native USDC and Circle’s Cross-Chain Transfer Protocol (CCTP) V2 are launching on Sei Network, strengthening its Layer-1 blockchain infrastructure. This development brings a regulated, fully reserved stablecoin and seamless crosschain liquidity to a fast-growing DeFi and gaming ecosystem. Sei users will soon access trusted USDC directly on the chain, improving performance and usability. At the same time, CCTP V2 will enable smooth asset transfers between Sei and other supported blockchains. Circle and the Sei Development Foundation confirmed the update on July 10.Native USDC on Sei Enhances Trust and OnboardingSei Network will now support native issuance of USDC directly from Circle. It replaces the previous reliance on Noble’s version through the Inter-Blockchain Communication protocol. While USDC from Noble will continue for now, the ecosystem plans to gradually shift liquidity to Circle-issued USDC.Native @USDC and CCTP V2 are coming to @SeiNetwork, bringing the world’s largest regulated stablecoin and frictionless crosschain transfers to Sei’s high performance Layer-1 blockchain.What native USDC brings: Regulated, fully reserved and redeemable 1:1 for US dollars… pic.twitter.com/R2xgP9guKx— Circle (@circle) July 10, 2025Native USDC on Sei will be redeemable 1:1 for U.S. dollars and offer institutional-grade access via Circle Mint. This means improved integration options for developers and businesses already using USDC across other chains. The move also sets up a trusted stablecoin base for gaming, payments, and decentralized finance use cases on Sei.CCTP V2, Circle’s updated cross-chain transfer protocol, is coming to Sei as part of this upgrade. It allows users to move native USDC between 13 supported chains using 156 different transfer routes.The system uses capital-efficient, direct burn-and-mint transfers. This method avoids wrapping tokens or liquidity fragmentation.As a result, developers can create cross-chain apps with efficient swaps, treasury tools, and onboarding systems that simplify the user experience. Circle says this supports a wider DeFi and Web3 market by removing friction between ecosystems.Sei’s Growth Sets the Stage for Stablecoin ExpansionSei Network has experienced strong growth in 2025, with its total value locked increasing by more than 188% year-to-date. It now holds over $600 million across more than 200 live applications, according to data as of July 10. The network’s Ethereum Virtual Machine compatibility and upcoming performance upgrades continue to attract developers.This growth, paired with the new USDC and CCTP rollout, positions Sei as a competitive Layer-1 chain for digital asset innovation. Circle’s integration signals rising confidence in Sei’s scalability and readiness to support more institutional liquidity and advanced use cases.According to Circle, the new integration will provide easy plug-and-play access for app developers. They can tap into USDC’s global reach while supporting fast, secure transfers and on/off-ramps through Circle’s ecosystem.Circle stated that the rollout is expected to drive usage across sectors including gaming, DeFi, and payments. The post Circle Brings Native USDC and CCTP V2 to Sei Network: Details appeared first on Blockonomi.