Pelvic pain often does not correlate with the severity of endometriosis, AKA, you can have Stage 1 and severe pain or Stage 4 with silent endo. An interesting study theorizes that pelvic pain is determined by the abundance of immune cells present in the peritoneum and not the number of endometriosis lesions. Collectively, our data suggest that the inflammatory profile of the peritoneal environment may be a better predictor of pain symptoms than the presence/volume of endometriosis lesions identified during laparoscopy. It also provides a theory as to why some previously pain-free women start experiencing chronic pain after lap surgery. In the context of the current results, we, therefore, speculate that surgical treatment itself could alter the peritoneal environment which raises the possibility that surgery could exacerbate pain symptoms in some patients.   submitted by   /u/Historical-Care70 [link]   [comments]