McCord, K. et al. Single-cell TCR mapping reveals spatially coordinated T cell states in head and neck cancer. Sci. Immunol. 11, eaec3133 (2026). This work presents the Xenium TCR technology used for validation of SPACER predictions.Article PubMed PubMed Central Google Scholar Tang, Y. & Wang, T. The rise of spatial TCR profiling: emerging technologies and open challenges. Sci. Immunol. 11, eaeg7517 (2026). This work introduces the Xenium TCR technology in a broader context that is relevant for our validation of SPACER.Article PubMed Google Scholar Axelrod, M. L. et al. T cells specific for α-myosin drive immunotherapy-related myocarditis. Nature 611, 818–826 (2022). This work reports the mouse model of myocarditis that we assessed in our study.Article PubMed PubMed Central Google Scholar Zhu, J. et al. Mapping cellular interactions from spatially resolved transcriptomics data. Nat. Methods 21, 1830–1842 (2024). This paper reports our previous work on developing a tool to study cell–cell communications in SRT data.Article PubMed Google Scholar Download references