The San Francisco 49ers are in a full-blown injury crisis, and wide receiver Mike Evans has become the biggest concern to date.Evans joined what was initially a stacked wide receiver room back in March, and signed a three-year deal worth up to $42.4 million to suit up with the Niners.Evans missed practice with a quad strain as San Francisco’s injury worries mountGettyBut he missed practice on Monday, and becomes the latest star to go down with an injury in San Francisco amid an intense training camp.“49ers WR Mike Evans is not practicing today due to a quad strain,” ESPN insider Adam Schefter confirmed, in a post shared Monday afternoon.The team has not announced the severity of their new wideout’s injury, nor have they shared a timetable for his return.But even a relatively minor quad strain can linger, or worsen, if a player tries to get back on the field too quickly.That means caution is particularly important for a veteran who is entering his 13th NFL season.Evans joins a long list of injured San Francisco receivers heading into week two of camp.Ricky Pearsall has already been lost for the season, after suffering a setback with his PCL injury that will see him undergo surgery.Christian Kirk, who also signed in free agency, strained his calf on the first day of camp and hasn’t featured since.Meanwhile, promising rookie De’Zhaun Stribling remains day-to-day with hamstring tightness.Such are the worries in the receiver room, that San Francisco has reunited with Deebo Samuel, and he will likely have a more significant role in Kyle Shanahan’s offense than initially expected.Pearsall is expected to miss the entire 2026 season as he undergoes surgeryGettyThe Niners have turned to a familiar face in Samuel as they battle an injury crisisGettyNiners lose rookie to torn ACL as injury list swellsBut the injury issues, unfortunately, stretch far beyond one position.Star tight end George Kittle has started camp on the active/PUP list with an Achilles issue.Running back Isaac Guerendo is recovering from a torn pectoral muscle, while fellow RB Jordan James is sidelined with fractured ribs.Third-round pick Kaelon Black also missed Monday’s practice with an adductor injury, but appears to have got off lightly, compared to another rookie.Defensive end Mikail Kamara went undrafted in 2026, but later signed with the 49ers.He was carted off the practice field Saturday, and waived with an injury designation one day later.Kamara suffered a torn ACL after being carted off from 49ers practiceGettyIt has now been revealed that Kamara suffered a torn ACL.According to NBC Sports, the Niners were expecting Kamara to compete for a roster spot as a pass rusher and a special teams contributor, but that now won’t happen.For San Francisco, the injuries continue to pile up, and a team that once had a bulging roster with high hopes heading into 2026 might find themselves calling in further reinforcements for a historic Week 1 game in Australia.