The Los Angeles Dodgers face off against the San Francisco Giants in the second game of their series on Wednesday night.Even after re-tooling their lineup, the San Francisco Giants have still struggled to play at a competitive level, grading out poorly in most offensive metrics.Unfortunately for the Giants, their struggles on offense will be on full display against the Los Angeles Dodgers as they battle it out against Shohei Ohtani who excels at avoiding contact while aggressively attacking the strike zone.With fifteen games taking place on Wednesday, there are plenty of prop bets and markets to wager on which you can read a detailed breakdown of them below.Best betting promos and sportsbooks for MLB prop betsFind the best promos and sportsbooks to use for today’s MLB prop bets.San Francisco Giants vs Los Angeles Dodgers (10:10pm, EST)Shohei Ohtani Under 1.5 Earned Runs (-115) at BetMGM SportsbookWhen on the mound, Shohei Ohtani has been dominant, kicking off his 2026 campaign with an ERA of 0.97, a WHIP of 0.811, and a FIP of 2.52.Ohtani’s brilliance can be attributed to his raw power and elite command of the ball, generating less than one Hit Against and more than one Strikeout per Inning Pitched in six games.In a NL West divisional matchup against the San Francisco Giants, expect Ohtani to build on his momentum by taking advantage of a lineup who ranks near dead last in Runs Scored, RBIs, On Base Percentage, and in OPS.Especially with his back end drastically reducing the amount of negative variance in his starts, surrounding Ohtani with a group who ranks fourth overall in Defensive Efficiency.Shohei Ohtani Over 17.5 Total Outs (-175) at Caesars SportsbookWith negative regression rearing its ugly head over the Giants Contact Rate, they will be unable to string together their Hits to advance their runners into scoring position, increasing the likelihood Ohtani goes the full length of his start on the mound.If the total on Ohtani’s Outs prop crosses through the key number of 17.5, then reduce the size of your wager.Tampa Bay Rays vs Toronto Blue Jays (7:07pm, EST)Tampa Bay Rays Team Total Under 3.5 (-140) at BetMGM SportsbookWhile the Tampa Bay Rays are currently in first place in the AL East division standings, their lack of production on offense holds them back from being a well rounded contender, fielding a lineup who ranks below league average in RBIs, Runs Scored, and in OPS.Their inability to score makes them vulnerable to prolonged scoring lulls, making it hard for them to match their opponents output.Heading into Wednesday night, expect the Rays struggles on offense to continue to be a thorn in their side as they face off against the Toronto Blue Jays Dylan Cease who is averaging an ERA of 2.58 and a FIP of 1.82 while generating more than one Strikeout per inning.For some more exposure, escalator bet the Rays team total by placing smaller wagers on their alternate unders at the best available odds across multiple sportsbooks.Cedric Mullins Under 0.5 Total Hit (-107) at Caesars SportsbookIn his first year with the Rays, Cedric Mullins has been unable to find his footing, generating less than one Hit per game, a .145 Batting Average, and a .421 OPS.With Cease creating Whiffs at a high rate while painting the strike zone, expect Mullins to continue to struggle at the plate and be held without a Hit against the Blue Jays pitcher.Los Angeles Angels vs Cleveland Guardians (1:10pm, EST)Los Angeles Angels Team Total Under 3.5 (-150) at BetMGM SportsbookEven with health back on their side, the Los Angeles Angels have been unable to round back into form, sitting in last place in the AL West.Their struggles on offense has played a major role in their slow start to the year, ranking in the bottom half of the board in Hit Rate and in On Base Percentage.With Parker Messick on the mound, expect the Angels to continue to struggle with getting on base, battling it out against an arm who is averaging a WHIP of 0.979 while generating less than one Hit Against per inning.Especially with the Cleveland Guardians narrowing the width of the Angels gaps in the outfield with their coverage, starting a group who ranks ninth in Fielding Percentage.About the authorKody MalstromKody Malstrom is a professional sports bettor and sports betting journalist with six years of experience covering a vast majority of sports. He covers football, basketball, hockey, baseball, and the UFC in written and video form.Born and raised in Michigan, Kody is a Detroit sports fan who spends all of his Sundays in the fall rooting for the Detroit Lions and Saturdays watching as much College Football as possible. In the winter, he shifts his focus to the Detroit Red Wings and Pistons while simultaneously rooting for his North Carolina Tar Heels.When he is not staring at betting markets, you can find Kody at the beach or snowboarding down a mountain, depending on the time of the year.Commercial content notice: Taking one of the sportsbooks offers featured in this article may result in a payment to talkSPORT. 21+. T&Cs apply. Gambling Problem? Call 1-800-GamblerResponsible gambling Remember to gamble responsiblyA responsible gambler is someone who:Establishes time and monetary limits before playingOnly gambles with money they can afford to loseNever chase their lossesDoesn’t gamble if they’re upset, angry, or depressedNational Council on Problem Gambling – https://www.ncpgambling.org/For help with a gambling problem, call the National Gambling Helpline on 1-800-522-4700 or go to ncpgambling.org/chatMost read in Sportsbooks USBest betting promos and sportsbooks for MLB prop bets [May 12, 2026]Best betting promos and sportsbooks for NBA prop bets [May 12, 2026]Best betting promos and sportsbooks for MLB prop bets [May 11, 2026]Best betting promos and sportsbooks for NBA prop bets [May 11, 2026]Best betting promos and sportsbooks for NBA prop bets [March 3, 2026]Best NBA prop bets today [November 5, 2025]