Acute myeloid leukemia (AML) is an aggressive blood cancer in which abnormal, immature cells build up in the bone marrow, disrupting the production of healthy blood cells. Now, a new study, led by Dr. José Luis Sardina's group at the Josep Carreras Leukaemia Research Institute (IJC), examines how two systems that help control normal blood cell development are connected: the chemical marks on DNA and the regulation of RNA, which carries instructions for making proteins. The work is published in the journal Science Advances.