Arsenal clash Slavia Prague in the Champions League on Wednesday night. And here at talkSPORT we have built our own Slavia Prague vs Arsenal bet builder on Betfred.Our Slavia Prague vs Arsenal bet builder selections Back our Slavia Prague vs Arsenal bet builder at 14/1 on SBK Add to your betslip HEREMikel Merino to scoreWHY: Mikel Arteta will look to rotate his side after the historic 1-0 away win over Liverpool at Anfield on Sunday evening.This may include bring back in the likes of Max Dowman, Eberechi Eze and Mikel Merino into the starting XI. Merino bagged two goals in this exact game last season as Arsenal ran out 3-0 winners in Prague in November 2025. The Spaniard is a bit of hybrid, which as his career’s developed has become his key unique selling point (USP).Arteta’s lieutenant on the field could well feast if Arsenal grab the game by the scruff of the neck. KEY STAT: In 2025/26, Merino scored four leagues goals from just nine shots on target. That’s 0.79 per 90 minutes. Christos Tzolis to assistWHY: Christos Tzolis returned to Arsenal’s starting lineup after a suffering a hamstring injury for Greece in the international break.The 24-year-old has four assists this season, but that feels a little light for a how well the Greek international has acclimatised back to English football. Statistically he’s made eight big chances across 362 minutes of league action. Arteta may choose to give Tzolis some more minutes as he continue his comeback from injury. Can the tricky winger make his mark on the match?KEY STAT: Christos Tzolis bagged 13 assists in the Jupiler Pro League in 2025/26 season.BTTS No and over 2.5 goalsWHY: Rewind 12 months and this fixture finished 3-0 to Arsenal. Both teams to score, NO? Tick! Over 2.5 goals? Tick!Despite shipping goals in the Champions League, Slavia have scored nine without conceding in their last two Czech League matches.Arsenal though, have been resilient at the back with Gabriel and Ezri Konsa forming a fearsome duo in William Saliba’s absence. If Arteta decides to keep with what’s working at centre-back it could well be a tough night for Slavia. KEY STAT: Arsenal have had five wins to nil in all competitions this season. Back our Slavia Prague vs Arsenal bet builder at 14/1 on SBK Add to your betslip HERE Slavia Prague vs Arsenal bet builder odds breakdownYou can find the best odds and market plays for international clash including our bet builder right here.Bet builder legBetfredMikel Merino to score anytime2/1Christos Tzolis to assist6/4BTTS No and Over 2.5 goals3/1Odds14/1 Back our Slavia Prague vs Arsenal bet builder at 14/1 on SBK Add to your betslip HERE Stats & news that matter for your Slavia Prague vs Arsenal betsStat #1: Slavia have not scored in their last five home matches against English clubs Stat #2: Arsenal have kept a clean sheet in all six away games vs Czech sides.Stat #3: Max Dowman (15y 308d) is the youngest player in Champions League history, first appearance at Slavia in 2025.Slavia Prague vs Arsenal match detailsDate: Wednesday 4th November 2026Time: 8pm GMTStadium: Fortuna Arena, Prague, UKLeague: Champions League, League Phase, Round 4 of 8TV Channel: TNT Sports – HBO MaxCommercial content notice: Taking one of the bookmaker offers featured in this article may result in a payment to talkSPORT. 18+. T&Cs apply.Remember to gamble responsiblyFind our detailed guide on responsible gambling practices and learn about:Reality checks and time limitsSelf-exclusionDeposit limitsGambling blocker toolsLimiting gambling contentHow to prevent underage gambling in the UKA responsible gambler is someone who:Establishes time and monetary limits before playingOnly gambles with money they can afford to loseNever chase their lossesDoesn’t gamble if they’re upset, angry or depressedGamcare – www.gamcare.org.ukFor help with a gambling problem, call the National Gambling Helpline on 0808 8020 133 or go to www.gamstop.co.uk to be excluded from all UK-regulated gambling websites.