Higher-quality evidence finds no causal link between prenatal acetaminophen use and neurodevelopmental disorders

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Various studies over the years have linked prenatal use of the pain reliever paracetamol (acetaminophen) with neurodevelopmental disorders such as autism and attention-deficit/hyperactivity disorder (ADHD) in children, but many of the studies were small, poorly designed or found only weak associations. A recent "umbrella" review in Developmental Medicine & Child Neurology reveals that the available scientific evidence does not support a causal relationship between paracetamol and neurodevelopmental disorders.