I need to make something abundantly clear, gentle reader. I ought perhaps to mention that we're tracking every Amazon Prime Day deal worth noticing if that's what you're after (and that the event is ongoing as I type), but, probably because of this big sale thing, I've been getting the question a lot and wanted to pin my colours to the mast. Right then: the Bose QuietComfort Ultra Earbuds (2nd Gen) and no other set of earbuds before or since these June 2025-issue buds still offer the best active noise cancellation on the market, provided your source device doesn't have a piece of fruit with a bite taken out of it etched on the back. I test earbuds as a full-time job and have done so since 2019 (I know, nice work, etc.), so it's my job to know these things. Other buds can offer better sound; I might point you towards Technics or Bowers & Wilkins here. And there are further buds I'd nudge you towards if you want novel features (here it is impossible not to note Samsung's own sets with live translation, as well as the ubiquitous ice-white offerings from Tim Cook's behemoth, some of which can monitor your heart rate). But for solid ANC, with music present and correct? Bose wrote the book on the technology, and Bose's buds are emphatically still the best. And although I'm contractually bound to tell you that right now, you can get the QCU Earbuds (2nd Gen) for a whopping £89 off, since they're now £209 rather than £299 at Amazon (and their lowest discount before today was to £249, so it's big), that's not why I'm here. • Browse the full Amazon Prime Day sale(Image credit: Future)No, I want to set the record straight once and for all. Until such time as a new set of earbuds swoops in and steals the spoils, this is the current, up-to-the-minute hierarchy. Yes, AirPods Pro can cut out the noise, and I've got a roundup of the top AirPods Prime Day deals if you need 'em. But unless you own an iPhone, those won't serve you as well — which is how Apple wants to keep it. If you're on Android, I maintain that the earbuds you're reading about now are hands-down the best. And they don't care what file format or streaming service you're listening to when it comes to offering the excellent head-tracked spatial stuff, too… Today's best Bose QuietComfort Ultra Earbuds (2nd Gen) deal Black Friday late last year was the first-ever saving I saw on this set of 5-star, 2025-release noise-cancelling earbuds, and that saw them drop to £249. Here's the thing: Bose products rarely see discounts, and that is because they basically walk all over anything else on the market for noise cancellation (except maybe Apple's AirPods Pro 3 — but if you don't own an iPhone, I don't recommend those, however good the deal). A lowest-seen fee on a truly excellent set of new earbuds from Bose? Yes please. View DealMy in-depth Bose QuietComfort Ultra Earbuds (2nd Gen) review is the place to go for my own even more detailed appraisal, but a cursory glance at the maximum five-star rating is perhaps all you need, along with this: They're just really, really good.Also, for those with particular interest, the 'Sonic Sangria' finish pictured above is in the deal (hurrah!), and please believe me when I tell you they get plenty of compliments when I wear them. (All other finishes are included in the deal, though.)I keep these buds beside my home desk, because the tree surgeons have been out in force recently (joy), and nothing cuts out chainsaw shrieks and the sound of falling timber quite like these. I also keep them here for when I'm testing the active noise cancellation efficacy of the competition. Yes, the Bose QCUE (2nd Gen) are essentially my reference product for ANC — a benchmark for what can be achieved in an in-ear design, if you've got a very special set of skills. With this particular second-generation model, you get wireless charging from the box (which wasn't so with the originals) and multi-point connectivity that works seamlessly, something the original QCU Earbuds also bizarrely lacked on their release.I also need to point out that I adore the Immersive audio profiles, which somehow mix device- and streaming service-agnostic spatial audio plus Bose's iconic noise-nixing to provide various vigorous, zealous, exciting soundstages for your movies or music.Some of the best earbuds on the market? Oh absolutely. And one of the best Prime Day earbuds deals I've seen? Oh, OK then — 100% yes.More Prime Day dealsAmazon Prime: get a 30-day free trialAmazon Devices: Fire, Ring & Blink from £13.99Amazon Haul: up to 30% offApple: up to 33% off AirPods & Apple WatchAppliances: up to 45% off Ninja & TefalBeauty: up to 60% off Philips & Oral-BEssentials: household goods from £5Fans: from £20Fashion: up to 50% offGaming: £90 off PlayStation 5Headphones: up to 50% off Beats & SonyLaptops: from £149Tablets: Samsung & Lenovo from £79.99Toys: up to 25% off Lego and ToniesTVs: from £129.99Vacuums: up to 40% off Shark & RoborockWearables: up to 30% off Garmin & Oura