Biomolecules are naturally occurring molecules that form the basis of living systems. They are widely used in the production of a diverse range of materials. One such widely used biomolecule is sulfated polysaccharide (SPS), which includes sugar molecules attached to sulfate groups. These are widely used in pharmaceuticals, cosmetics, and functional materials due to their unique physical and biological properties. However, commercially available SPSs are usually derived from animal or marine sources, which raises concerns about their environmental impact, calling for alternative SPS production methods.