Tottenham Hotspur have been handed a boost ahead of their trip to Old Trafford, as it has emerged that the Lilywhites could be facing an extremely depleted Man United side.Tottenham’s Dutch duo, Jan Paul van Hecke and Micky van de Ven suffered injury scares during the international break, which led to concerns among Spurs fans about their potential unavailability for Saturday’s clash.However, it has subsequently emerged that neither Spurs centre-back has a serious injury, and both of them could be in line to feature at Old Trafford.Spurs are without Pedro Porro, Mykhailo Mudryk, Wilson Odobert and Xavi Simons, and while Dejan Kulusevski has made good progress since returning to training, it remains unclear when he will be named in a Tottenham matchday squad.Photo by SpursWebNine Man United players are doubtful to be involved against TottenhamThe Sun have revealed that nine Man United stars could face late fitness tests ahead of Saturday’s game, including Marcus Rashford and Kobbie Mainoo, who both withdrew from the England squad.Patrick Dorgu returned to United after sustaining an injury in Denmark’s 2-0 Nations League win against Wales last week, and remains a doubt for the upcoming clash.Noussair Mazraoui was forced off in Morocco’s Africa Cup of Nations victory against Lesotho and did not feature in his country’s 1-1 draw with Mali on Sunday.Bruno Fernandes was not involved in Portugal’s 2-1 triumph against Norway in Oslo on Sunday, with the attacking midfielder managing an injury over the last few weeks.Benjamin Sesko did not join the Slovenia squad during the international break due to his injury, and he is ‘highly unlikely’ to be fit for the clash against Spurs. However, there is optimism at United that Amad, who is yet to feature this season, will make the bench against De Zerbi’s side.Finally, it is revealed that back-up goalkeeper Karl Darlow also pulled out of the Wales squad due to an injury while third-choice keeper Tom Heaton has been sidelined with a hamstring problem for the last two months. Young goalkeeper Dermot Mee would be in line to make the bench for the clash on Saturday.Will James Maddison make his first start of the season?Spurs fans will be hoping that the three-week break has allowed James Maddison to build up his fitness and that the attacking midfielder is ready to start matches in the Premier League.The England international last competitive start for Tottenham came in May of last year, in the first leg of the UEFA Europa League semi-final first leg against Bodø/Glimt.Mohammed Kudus has not started a Premier League fixture since the start of January, and the winger stayed back at Hotspur Way during the international break to work on his fitness after withdrawing from Ghana’s squad.READ MORE: Tottenham will laugh Juventus out of N17 with wild Destiny Udogie valuationThe post Nine Man United players face late fitness test to face Tottenham Hotspur appeared first on Spurs Web.