Alexander Isak will return to Newcastle for the first time since forcing an exit from the club in Liverpool’s season opener.Isak and his Reds teammates begin their Premier League campaign with a trip to St. James’ Park on August 23.Isak is going to return to take on Newcastle for the first time since leavingGettyThe match is also new manager Andoni Iraola‘s first competitive outing in charge after he replaced Arne Slot in the dugout.Liverpool finished fifth in the top-flight last season, with Slot paying the price for what was a disappointing title defence.They managed to qualify for the Champions League, and will be desperate to be back challenging for top spot this term.Some new faces have arrived and club legends have departed, with Iraola starting fresh on the road against Newcastle.And talkSPORT.com has taken a look at how they could line up for the match.Isak’s awkward returnOne man who has a point to prove is Isak – and he’s looking set to start up front for the Reds against his former club.But he’s going to have to play in some tough conditions in Newcastle, as he certainly won’t be getting a good reception.Isak left the Magpies last summer in a British transfer record move, signing for Liverpool for a whopping £125million.He did so in controversial fashion, going on strike to force a transfer and releasing a shock statement demanding to leave the club.Those actions will have destroyed any relationship with the Newcastle supporters, so Isak won’t be welcomed back.Isak is unlikely to get a nice reception back at St. James’ Park on August 23AFPIt will remain a big moment for the Sweden international though, after going through multiple injury issues last season, including a broken fibula that saw him sit out for five months.He only played 14 Premier League games for Liverpool in his debut campaign, missing 30 matches for club and country.However, after a full pre-season, Isak is regaining his fitness and seems sure to be leading the line in his side’s opener.How will Liverpool line up on opening day?Iraola has been playing in a 4-2-3-1 formation in pre-season with Liverpool, similarly to former manager Slot.Isak will be the lone striker as Hugo Ekitike continues his recovery after rupturing his Achilles – and there will be a talented three in behind him, including a seemingly settled Florian Wirtz.Wirtz struggled to show his best in his first Premier League season, only scoring five goals and providing three assists in total.Iraola will hope for a winning start to his tenure as Liverpool managerGettyWirtz looks to be showing his best heading into the new campaignGettyBut in the friendlies leading up to the new campaign, he’s already scored twice and looks very sharp as the No.10.Out wide will likely be rising talent Rio Ngumoha, who was the subject of calls for more regular football last term. Now, he’s featured throughout pre-season and could be set to start, with Mohamed Salah‘s position up for grabs. New signing Victor Munoz could also be a contender to play there, but he only played his first minutes on August 9.On the left, Cody Gakpo is expected to start, despite being linked with a move away from the club to Tottenham this summer.Meanwhile, it seems Ryan Gravenberch and Dominik Szoboszlai will form the midfield, with Alexis Mac Allister not long back from World Cup duty with Argentina.Recent arrival Araujo may have been thrown straight into the Liverpool defenceGettyTeenage star Trey Nyoni could also take some minutes in that position this season, along with Wataru Endo and Curtis Jones, should the latter stay at the club amid exit talks.In defence, Jeremie Frimpong will be at right-back, with centre-back Virgil van Dijk and left-back Milos Kerkez certain to be joining him.However, Jeremy Jacquet faces a race against time to be fit to make his Premier League debut in his side’s season opener.Jacquet has not played a game since February due to injury, so it may take him a while to get up to speed with the team. That means Ronald Araujo could come straight into the starting XI, having just signed on loan from Barcelona, with Joe Gomez and Giovanni Leoni both still carrying injuries.But young defenders Ifeanyi Ndukwe and Luke Chambers could potentially push for a start in place of Araujo after picking up plenty of minutes in pre-season.This could be how Liverpool start against Newcastle next week