Nature Materials, Published online: 14 August 2026; doi:10.1038/s41563-026-02711-6Magnetotransport measurements on numerous samples of monolayer–multilayer (1 + N) rhombohedral graphene reveal a high-Chern-number quantum anomalous Hall effect with Chern number C = N. Further, in twisted Bernal bilayer–rhombohedral tetralayer graphene, a displacement-field-driven topological phase transition between C = 3 and C = 4 states is demonstrated.