A motorcyclist has been rushed to hospital after a crash with a vehicle on Highway 401 in Mississauga.Ontario Provincial Police were called to the eastbound express lanes near Winston Churchill Boulevard around 4 p.m. Monday. A 53-year-old man was taken to hospital with serious, life-threatening injuries.It’s unknown whether anyone else was injured in the crash.The eastbound express lanes are closed from Winston Churchill to Mavis Road and the investigation is still ongoing.