Officially getting the 2026/27 Serie A campaign underway on Saturday night, Napoli will travel to Liguria when they meet Genoa.With Europe’s elite domestic leagues making their respective returns this weekend, there are plenty of eye-catching betting promotions available.Verdict: Napoli winBest Odds: 19/20Bookmaker: 1xBetGenoaStarting with the hosts, while Genoa might have eventually maintained their Serie A status with time to spare last season, the Griffins are desperately hoping for some essential stability this time around. Spending the whole of the 2025/26 campaign scrapping it out at the foot of the table, Daniele De Rossi’s men will be bracing themselves for a stern examination when they open proceedings on Saturday night. Falling to an action-packed 3-2 loss when they welcomed Napoli to the Stadio Luigi Ferraris for a Serie A showdown back on February 7th, Genoa do hold a worrying record against the former Italian champions. In fact, De Rossi’s side are unbeaten in all of their previous eight consecutive battles against Napoli across all competitions (five defeats, three draws).Genoa Team NewsBagging a Coppa Italia strike against Ascoli last week on what was his competitive Genoa debut, summer recruit and former AC Milan striker Lorenzo Colombo will spearhead Di Rossi’s charge in the final third.Ahead of Saturday’s Serie A opener, Genoa have reported a clean bill of health. Making a permanent switch from Dutch giants Feyenoord last year, Netherlands international Justin Bijlow will start between the sticks this weekend.NapoliAs for the visitors, relinquishing their Serie A crown last season as they were eventually forced to settle for a silver medal finish among Italy’s elite, Napoli have certainly got a new era underway over the summer. Now under the guidance of Max Allegri, the former Juventus boss has some serious expectations on his experienced shoulders. Signing off the 2025/26 campaign with a 1-0 victory against Udinese on May 24th, Saturday’s guests will be looking to make an opening weekend statement here. Likewise, landing that frantic 3-2 win when they last travelled to the Stadio Luigi Ferraris back in February, Allegri’s side have also registered 10 points from their previous four Serie A trips to Genoa. In fact, Napoli have also suffered just a sole top-flight defeat in Liguria since way back in January 2012.Napoli Team NewsMaking his move to Naples a permeant switch this summer, former Manchester United striker Rasmus Hojlund will spearhead Allegri’s attack here. However, ex-Ajax star David Neres remains on the sidelines with a long-term ankle issue and won’t play any part this weekend.Signing off his pre-season preparations with a friendly strike against Greek outfit Aris last week, Scotland international Scott McTominay could play a leading role in the middle of the park.Genoa vs Napoli Key Factors to ConsiderWhen Genoa and Napoli last met for a Serie A showdown back on February 7th, Saturday’s guests claimed an action-packed 3-2 victory in Liguria.In fact, Napoli are unbeaten in all of their last eight straight meetings against Genoa across all competitions (five wins, three draws).Napoli have suffered just a sole top-flight defeat in Liguria since way back in January 2012.Genoa lost three of their final four Serie A showdowns at the Stadio Luigi Ferraris last season.Each of the last six meetings between Genoa and Napoli have finished with both teams finding the net.ConclusionWith their sights set on recapturing their Serie A crown this season, Napoli will be desperate to open proceedings with an immediate flurry here. Landing a rollercoaster 3-2 victory when they last travelled to the Stadio Luigi Ferraris back in February, Allegri’s new squad do hold a dominant record against Saturday’s hosts. In fact, along with registering 10 points from their previous four Serie A battles, they have also tasted just a sole defeat in Liguria over the past 14 years. Two camps who are expected to be scrapping it out at opposite ends of the Serie A standings this season, we are backing an away victory in Liguria.Verdict: Napoli winBest Odds: 19/20Bookmaker: 1xBetThe post Prediction: Genoa vs Napoli appeared first on SoccerNews.