Targeting fat-cell enzyme offers potential strategy to reduce obesity and cancer risk

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Obesity touches countless lives across the country and can lead to many other health complications. From August 2021 to 2023, the prevalence of obesity in adults in the U.S. was more than 40%. Research published in Science Advances, led by scientists at VCU Massey Comprehensive Cancer Center, found that targeting fat cells specifically with inhibitors of the enzyme sphingosine kinase 2 could be a new strategy to combat obesity and lower the risk of its comorbidities like cancer.