Marin Cilic has withdrawn from the 2026 US Open through injury.The Croatian star, who was the men’s singles champion at Flushing Meadows in 2014, has pulled out on the eve of his opening match.Cilic has pulled out of this year’s US OpenGettyCilic was due to face the 23rd seed Andrey Rublev in the first round on Monday.However, he is not fit enough to compete and has been replaced by lucky loser Otto Virtanen.This year’s 19th seed Casper Ruud is another withdrawal due to injury, with Frenchman Arthur Gea the lucky loser to fill in for him.Cilic misses out on latest US Open appearanceThree-time Grand Slam finalist Cilic became a surprise US Open title-winner 12 years ago when he beat Kei Nishikori in the final.Victory came in his sixth outing and made him the first male Croatian major winner since Goran Ivanisevic, who won Wimbledon in 2001.Cilic reached the semi-finals a year later but could not replicate his prior success, which is the only Grand Slam triumph of his career.Had he been fit to play this year, the 37-year-old would have played at his 16th US Open.He is also missing a Grand Slam tournament for the first time in 2026.Cilic reached the third round at the Australian Open but was knocked out by Ruud in a four-set clash.First round exits at the French Open and Wimbledon then followed.Cilic beat the odds to win the US Open in 2014GettyWhat has happened at the US Open so far?Both the men’s and women’s singles events commenced on Sunday, but the tournament got up and running last weekend.Mixed doubles was the main attraction during Fan Week with a star-studded line-up of pairings.Carlos Alcaraz, who missed the past two Grand Slams, played with the legendary 23-time major women’s singles champion Serena Williams.However, they were knocked out during the quarter-finals, with Czech pair Karolina Muchova and Jakub Mensik winning the title.Home favourite Jessica Pegula won her first round singles match against Elena-Gabriela Ruse, with Coco Gauff facing Zeynep Sonmez at midnight UK time on Wednesday.Alcaraz begins his title defence on Monday when he takes on Roman Safiullin, with this year’s total prize pot standing at $108million.