League Two Grimsby Town host Premier League giants Manchester United in the EFL Cup tonight at Blundell Park.Grimsby Town vs Man United best betsBenjamin Sesko to score and get 3+ SOT at 5/2 on MidniteManchester United to win and over 3.5 goals at 1/1 with ToteGrimsby Town vs Man United latest oddsFind the latest Grimsby Town vs Man United betting odds here. Odds are provided by Midnite and are subject to change.Grimsby Town – 16/1Draw – 13/2Manchester United – 1/8Get free bets on the football action!Grimsby Town vs Man United predictionsGrimsby Town will be hoping to make the most of this challenge up against this Premier League side.It could be a classic tale of David vs Goliath as all cup ties like to bill it as and it has the makings of it judging by the odds alone.Grimsby sit in 4th in League Two and face Man United who are 16th in the Premier League, a huge gap between the two in all aspects.Grimsby Town vs Man United betting tipsSesko can make most of startThe Red Devils have clearly wanted to turn a corner this season with the trust fully in Ruben Amorim to implement his system despite finishing 15th in the Premier League last season.In the summer they completely transformed their attacking outlet but have yet to really showcase it.This could be the time for new signings Benjamin Sesko, Matheus Cunha and Bryan Mbeumo to really get some practice in gelling together, to get plenty of chances in front of goal.I’d imagine Man United will send out a few youngsters tonight though to give them a run out.However, Sesko didn’t start against Fulham or against Arsenal in their opening two games in the Premier League so it seems likely he will be among the starters.Bet on Benjamin Sesko to score and get 3+ SOT at 5/2 on MidniteMan United to fend off GrimsbyGrimsby will put in a big effort tonight but they may struggle to keep the chances for Manchester United out.If United to get the lead in the first half it could open things up even more allowing them to continue to their barrage of attacks.You wouldn’t want to rule out a bit of a wait for the first goal though.Bet on Manchester United to win and over 3.5 goals at 1/1 with ToteGrimsby Town vs Man United predicted lineupsGrimsby Town expected lineup: Pym; Rodgers, Warren, McJannet, Staunton; Amaluzor, McEachran, Turi, Khouri, Burns; KabiaManchester United expected lineup: Onana; Shaw, Fredricson, Maguire; Dalot, Mainoo, Ugarte, Dorgu; Fernandes, Cunha; SeskoWhere to watch Grimsby Town vs Man UnitedLocation: Blundell Park, Cleethorpes, England.Date & Time: Wednesday, 27th August 2025, 8pm.TV Channel: ITVX.More EFL Cup predictionsFind more predictions and betting tips from our expert punters in our match previews on the Premier League, Championship, EFL, cup competitions and more!Commercial content notice: Taking one of the bookmaker offers featured in this article may result in a payment to talkSPORT. 18+. T&Cs apply. GambleAware.orgRemember to gamble responsiblyA responsible gambler is someone who:Establishes time and monetary limits before playingOnly gambles with money they can afford to loseNever chase their lossesDoesn’t gamble if they’re upset, angry or depressedGamcare – www.gamcare.org.ukGambleAware – www.gambleaware.orgFind our detailed guide on responsible gambling practices here.For help with a gambling problem, call the National Gambling Helpline on 0808 8020 133 or go to www.gamstop.co.uk to be excluded from all UK-regulated gambling websites.Free Bet OffersSee all the best free bets and betting offers available in the UK over at our dedicated pageSee all free bets18+ gambleaware.org. T&Cs apply