New UTI drug approved after almost three decades | The IndependentNotifications can be managed in browser preferences.Jump to contentIndependentNext articleIndependent Bulletin homepageSocial PartnerWe are 8 logo (opens in a new tab)AllNewsSportCultureLifestyleStorm NewtonThursday 28 August 2025 07:25 BSTDoes drinking cranberry juice prevent UTIs? Doctor separates fact from fictionGepotidacin, also known as Blujepa, has been approved for NHS use in the UK to treat uncomplicated urinary tract infections.This marks the first new type of oral antibiotic for UTIs to be approved in nearly three decades, offering a new option for women over 12 with recurring infections.The drug works by blocking bacterial enzymes, preventing replication, and its targeted mechanism makes it more difficult for bacteria to develop resistance.Clinical trials indicate that gepotidacin is as effective as nitrofurantoin, the current frontline antibiotic for uncomplicated UTIs.Before widespread NHS prescription, the drug's cost-effectiveness will be evaluated by the National Institute for Health and Care Excellence.In fullBreakthrough hailed as ‘crucial’ UTI drug gets green light for NHS useThank you for registeringPlease refresh the page or navigate to another page on the site to be automatically logged inPlease refresh your browser to be logged in