Researchers at the Regensburg Center for Biochemistry (RCB) and the Regensburg Center for Ultrafast Nanoscopy (RUN) at the University of Regensburg are obtaining unique insights into the structure, dynamics and function of dynamic components of the exosome, an RNA-degrading molecular machine in the cell. The results not only provide biological information on RNA degradation but are also a methodological milestone in structural elucidation of biomolecules.