West Ham and Leeds will put relegation fears aside with an FA Cup Wembley semi-final up for grabs on Sunday afternoon.Both these sides are battling to remain in the Premier League but could the cup be a welcome distraction to the relegation strain?A cup semi-final at Wembley is on the line for whoever emerges the victor here. Will one team throw caution to the wind to seal a big day out in the capital?West Ham vs Leeds best betsTo win the tie – West Ham – 10/11 with MidniteWest Ham to qualify on penalties – 9/1 BOYLE SportsTotal Goal O/U 2.5 goals – 8/11 BOYLE SportsWest Ham vs Leeds latest oddsFind the latest West Ham v Leeds betting odds here. Odds are provided by BOYLE Sports and are subject to change.West Ham – 13/10Draw – 12/5Leeds – 13/8West Ham vs Leeds: Betting tips, predictions, lineups, how to watch and best bets on International friendlyWest Ham vs Leeds predictionsCould the FA Cup actually represent the momentum shift or the continuation of form both these clubs need? One, to help avoid relegation in the Premier League, but also to keep the fans onside and have something positive to show for the season. The Hammers up tick in form actually came after their extra-time win over QPR in the FA Cup third round. Which sparked this run to the quarter finals and dragging themselves to within a point of safety in the league. This game could come too soon for Crysencio Summerville to return from the injury he picked up in the penalty shootout victory over Brentford in the last round. The Dutchman provided the jump-start the East London club have needed to become a competitive outfit in 2026.Nuno Espirito-Santo will have to decide to who to play up front with January signings Taty Castellanos and Pablo Felipe offering different options in attack.Daniel Farke finally got his cup home draw he so craved, ironically against his former side Norwich in the last round. The Whites produced one of their best performances of the season winning 3-0 against the Championship outfit.Leeds have been drawing their way to Premier League safety, but they’re not out of the woods yet. Farke may yet again shake up his starting eleven to give his fringe players opportunities in the final part of the season. This may offer starting hopes to Wilfried Gnonto, Joel Piroe and Facundo Buonanotte. Forward Noah Okafor will be touch and go for this, Farke may opt to rest him for the Manchester United league game.Will both these manager’s see the cup as a welcome distraction with just two wins needed to make the final. West Ham vs Leeds betting tipsWest Ham’s home advantage could prove the telling factor in this quarter final clash. Two of their three wins in this year’s competition this season have come at the London Stadium, including the penalty shoot-out victory against Brentford.Espirito Santo’s side may have to be prepared for this one to go the distance too. Leeds who are also not out of the woods of relegation yet, have the added benefit of not playing again until Monday 13th, a whole eight days break. This may mean Farke goes with a stronger line-up than he might have done so, with the carat of a trip to Wembley at the end of it. West Ham vs Leeds predicted lineupsWest Ham expected lineup: Areola; Scarles, Mavropanos, Disasi, Wan-Bissaka; Fernandes, Kante, Soucek; Bowen, Wilson, Pablo Leeds expected lineup: Perri; Struijk, Bijol, Rodon, Ampadu, Justin, James; Stach, Aaronson; Nmecha, PiroeWhere to watch West Ham vs LeedsLocation: London Stadium, London, England.Date & Time: Sunday, 5 April March 2026, 4:30pm.TV Channel: TNT Sports 1, TNT Sports Ultimate, HBO MaxTo win the tie – West Ham – 10/11 with MidniteWest Ham to qualify on penalties – 9/1 BOYLE SportsTotal Goal O/U 2.5 goals – 8/11 BOYLE SportsMore FA Cup predictionsFind more predictions and betting tips from our expert punters in our match previews on the FA Cup, Premier League, Champions League, Championship, the World Cup and much more!Commercial content notice: Taking one of the bookmaker offers featured in this article may result in a payment to talkSPORT. 18+. T&Cs apply. GambleAware.orgRemember to gamble responsiblyA responsible gambler is someone who:Establishes time and monetary limits before playingOnly gambles with money they can afford to loseNever chase their lossesDoesn’t gamble if they’re upset, angry or depressedGamcare – www.gamcare.org.ukGambleAware – www.gambleaware.orgFind our detailed guide on responsible gambling practices here.For help with a gambling problem, call the National Gambling Helpline on 0808 8020 133 or go to www.gamstop.co.uk to be excluded from all UK-regulated gambling websites.Free Bet OffersSee all the best free bets and betting offers available in the UK over at our dedicated pageSee all free bets18+ gambleaware.org. T&Cs apply