Week 10 of the NFL season gets underway tonight with an AFC West clash between the Denver Broncos and the Las Vegas Raiders.Denver Broncos v Las Vegas Raiders best betsDenver -8.5, 43+ points, Bo Nix 2+ passing touchdowns, JK Dobbins 80+ rushing yards at 6/1 with BetMGMDenver Broncos v Las Vegas Raiders latest oddsFind the latest Denver Broncos v Las Vegas Raiders moneyline betting odds here, odds courtesy of BetMGM and are subject to change.Denver Broncos – 1/5Las Vegas Raiders – 15/4Denver Broncos v Las Vegas Raiders predictionsDenver Broncos head into tonight’s Week 10 curtain raiser clash as overwhelming favourites for victory in front of their home fans as they look for their seventh consecutive win to further enhance their bid for just a second play-off appearance in 10 years.The Colorado side currently boast the joint-best record in the NFL, with their 7-2 start to the season their best since their Super Bowl winning season back in 2015.Sean Payton’s side also hold the current best win streak in the league, making it six victories in a row following their narrow 18-15 over Houston last week, and has also involved notable wins over Dallas, Cincinnati and the the reigning Super Bowl champions, Philadelphia.The Broncos currently boast a 4-0 record at Empower Field at Mile High this season, meaning they have now won their last nine matches in their home stadium since October 2024.The Las Vegas Raiders make the trip to Denver enduring a less successful season, currently with a 2-6 record ahead of tonight AFC West clash.Pete Carroll got the better of the New England in Week 1 and have since fallen to six defeats in their last seven matches after last week’s agonising overtime loss to Jacksonville on the back of their bye week, only beating Tennessee in that time.The Nevada side will need to start winning pronto in order to end their three-year wait for a play-off appearance, with nine wins generally needed, leaving the Raiders needing at least seven wins from their nine remaining games.Denver should secure a fairly comfortable victory over Las Vegas tonight as they look to tighten their grip on the AFC West and aim for the number one seed, I’m predicting a 26-17 Broncos victory.Denver Broncos v Las Vegas riaders betting tipsNix and Dobbins take Broncos to seven in a rowThe Broncos, chasing the play-offs and with their best start to the league since they last won the Super Bowl, will be looking to put their divisional rivals to the sword at Empower Field, where they’ve won their last nine games.Only two quarterbacks have thrown more touchdown passes in the NFL this season than Bo Nix for Denver, while running back JK Dobbins is currently fifth for most rushing yards, just five short of the 700 mark heading into Week 10.Denver -8.5, 43+ points, Bo Nix 2+ passing touchdowns, JK Dobbins 80+ rushing yards at 6/1 with BetMGMHow to watch Denver Broncos v Las Vegas RaidersLocation: Empower Field at Mile High, DenverDate and time: Friday 7th November 2025, 1:15amHow to watch: Sky Sports Main Event, Sky Sports NFL, Sky Sports Ultra HDRMore NFL predictionsFind more predictions and betting tips from our expert punters in our match previews on the NFL as well as other sports around the globeCommercial content notice: Taking one of the bookmaker offers featured in this article may result in a payment to talkSPORT. 18+. T&Cs apply. GambleAware.orgRemember to gamble responsiblyA responsible gambler is someone who:Establishes time and monetary limits before playingOnly gambles with money they can afford to loseNever chase their lossesDoesn’t gamble if they’re upset, angry or depressedGamcare – www.gamcare.org.ukGambleAware – www.gambleaware.orgFind our detailed guide on responsible gambling practices here.For help with a gambling problem, call the National Gambling Helpline on 0808 8020 133 or go to www.gamstop.co.uk to be excluded from all UK-regulated gambling websites.Free Bet OffersSee all the best free bets and betting offers available in the UK over at our dedicated pageSee all free bets18+ gambleaware.org. T&Cs apply