World’s first gene-edited pig kidney transplants begin in clinical trial | The IndependentNotifications can be managed in browser preferences.Jump to contentIndependentSwipe for next articleIndependent Bulletin homepageDownload ourSocial PartnerWe are 8 logo (opens in a new tab)AllNewsSportCultureLifestyleLauran NeergaardTuesday 04 November 2025 02:32 GMTGene-edited pig lung transplanted into patientThe world's first clinical trial involving the transplantation of gene-edited pig kidneys into human recipients has commenced.United Therapeutics announced the initial procedure was successfully carried out at NYU Langone Health, marking a significant advancement in xenotransplantation.The trial, led by Dr Robert Montgomery, will initially involve six participants and could expand to 50, with another company, eGenesis, also preparing a similar trial.Previous “compassionate use” transplants have shown mixed results, with pig kidneys lasting up to 271 days before recipients returned to dialysis.This research aims to address the critical shortage of donor organs, with over 100,000 people in the U.S. awaiting transplants, by genetically altering pig organs to be more compatible with human immune systems.In fullGroundbreaking pig organ transplant trial gets underwayThank you for registeringPlease refresh the page or navigate to another page on the site to be automatically logged inPlease refresh your browser to be logged in