Barcelona were knocked out of the Champions League last week, but they are well positioned to retain the La Liga title. Ahead of the midweek round of games in Spain, Hansi Flick’s team are nine points clear of Real Madrid.Will Barca come out on top when Celta Vigo visit Catalonia, or might we see a surprise result on Wednesday?Barcelona/Barcelona half-time/full-time – 8/11 with BoyleSportsOver 3.5 goals – 10/13 with CasimbaLamine Yamal to score any time – 10/11 with SBKBarcelona vs Celta Vigo head to head overviewDate: Wednesday 22nd April.Kick-off: 8.30pm.Venue: Camp Nou, Barcelona, Spain.Where to watch: Premier Sports 1.Referee: TBC.VAR: Yes.Last meeting: 9th November 2025; Celta Vigo 2-4 Barcelona.Last 10 matches: Barcelona – 6 wins; Celta Vigo – 2 wins; Draws – 2.Favourite to win: Barcelona.Barcelona vs Celta Vigo predicted lineupsBarcelona expected lineup: J. Garcia; Araujo, Cubarsi, Martin, Bale; E. Garcia, Pedri; Yamal, Lopez, Gavi; Torres.Celta Vigo expected lineup: Radu; Nunez, Aidoo, Alonso; Rueda, Lopez, Vecino, Carrera; Antanon, Duaran, Swedberg.Barcelona vs Celta Vigo predictionsBarcelona have not won the Champions League since 2015 and they will not get their hands on the trophy this season either.The club’s dreams of continental glory were extinguished last week. A 2-1 victory away to Atletico Madrid was a good result in isolation, but Barcelona ultimately lost the quarter-final 3-2 on aggregate.Disappointment is still in the air at the Camp Nou, but Barca can at least console themselves with the fact they are odds-on favourites to win the La Liga title.Real Madrid are set to play on Tuesday evening, 24 hours before Barcelona face Celta Vigo. Even if Madrid beat Alaves as expected, they will be six points behind the Blaugrana having played a game more.Back-to-back titles cannot be sniffed at, especially for a manager like Hansi Flick who is only in his second season as Barcelona boss. Four victories from their final seven games would almost certainly be enough for Barca to get over the line, although they might not even need that many depending on how Madrid fare in the coming weeks.Celta Vigo are fighting for points for their own reasons. They are sixth in the standings at present, two points behind Real Betis in fifth.Spain may yet gain an additional Champions League qualification berth, in which case a top-five finish would give Celta a seat at Europe’s top table next term.That is quite the incentive for Claudio Giraldez’s charges, who are nevertheless huge underdogs for Wednesday’s clash in Catalonia.Barcelona vs Celta Vigo betting tipsBarcelona are closing in on the La Liga title as they prepare to face Celta Vigo on Wednesday.Comfortable night for Barcelona?Celta Vigo have the quality to give Barcelona something to think about, but we still expect the home team to have too much for their opponents.Barcelona have won 16 out of 16 home league games this term, so it will be very difficult for Celta to get anything from this trip to the Camp Nou.Flick will want to see his team make a fast start as they seek to bounce back from last week’s Champions League exit.Barcelona have the best first-half record in the division and they should be ahead at the interval against Celta. Tip Barcelona/Barcelona in the half-time/full-time market at 8/11 with BoyleSports Celta Vigo will make this funCelta Vigo have a real opportunity to qualify for Europe this season. At the very least, they are on course for a second consecutive top-half finish for the first time in a decade.Celta will not simply sit back and play passively on Wednesday. They have the third-best away record in the league, so the visitors will try and get something from this match.Celta are the seventh-highest scorers in La Liga despite taking the fifth-fewest shots. The opportunities they create tend to be good ones.Barcelona’s matches contain the most goals in the league on average, so this promises to be an entertaining affair. Back over 3.5 goals at 10/13 with Casimba Lamine Yamal in fine fettleLamine Yamal got on the scoresheet in the 2-1 defeat of Atletico Madrid last time out, as the teenage starlet continued his excellent recent form.Yamal has either scored or assisted four goals in Barcelona’s last two outings, and Celta Vigo will have their hands full as they attempt to keep him quiet this week.The forward has been terrific since the international break last month and he will likely have a major role to play against Celta.Yamal has scored 15 league goals this term and he will be targeting 20 before the conclusion of the campaign. Go for Lamine Yamal to score any time at 10/11 with SBK Barcelona vs Celta Vigo latest oddsFind the latest Barcelona vs Celta Vigo betting odds here. All odds are provided by our recommended football bookmakers and are subject to change.More La Liga predictionsWe have plenty more La Liga predictions and picks – find our latest betting tips from expert punters in our match preview overview.Important historical facts about Barcelona vs Celta Vigo for bettingThere have been 28 goals in the last six games between Barcelona and Celta Vigo. Hansi Flick’s side need three more home wins to finish the season with a 100 percent record in front of their own fans.Celta Vigo have collected 61.37 percent of their points away from home, the highest figure in La Liga.About the authorGreg LeaGreg Lea is a freelance football writer from London. He predominantly covers the Premier League and has had work published by the Guardian, FourFourTwo, ESPN and others.Follow Greg on X: @GregLeaFootballCommercial content notice: Taking one of the bookmaker offers featured in this article may result in a payment to talkSPORT. 18+. T&Cs apply.Remember to gamble responsiblyA responsible gambler is someone who:Establishes time and monetary limits before playingOnly gambles with money they can afford to loseNever chase their lossesDoesn’t gamble if they’re upset, angry or depressedGamcare – www.gamcare.org.ukFind our detailed guide on responsible gambling practices here.For help with a gambling problem, call the National Gambling Helpline on 0808 8020 133 or go to www.gamstop.co.uk to be excluded from all UK-regulated gambling websites.Most read in BettingBag up to £40 in free bets with SBK's brand new offer!Leicester v Hull prediction, betting tips and bet builder - Can Tigers down Foxes?Best horse racing betting sites April 2026 - Bonuses, tips & oddsBest Online Casinos in the UK for 2026: Find the best Gamstop Casino SitesFree spins on sign up UK (April 2026) - Casinos with the best free spins bonusesBest new betting sites in the UK for April 2026