Atletico Madrid and Arsenal play the first leg of their Champions League semi-final at the Metropolitano on Wednesday evening.The duo previously duked it out in the league phase when, after heading into the break goalless, the Gunners produced a flurry of four goals in 13 second-half minutes to claim a 4-0 victory.They are the only unbeaten team left in the Champions League, but have appeared nervous in recent months and the hostile atmosphere in the Spanish capital may only add to their anxiety.GET UP TO £40 IN FREE BETS WHEN YOU BET ON THE FOOTBALL WITH talkSPORT BETAtletico Madrid vs Arsenal betting tipsDraw Antoine Griezmann to score Koke to be bookedWas 30/1 now 33/1Atleti and Arsenal may accept a drawMuch has been made of Atletico’s transformation into a more attacking unit than in the early years of Diego Simeone’s reign and their 34 goals scored is behind only Paris Saint-Germain and Bayern Munich.They have also conceded 26 times, a significant number when compared to Arsenal’s five allowed, but Wednesday may be an occasion when they wind back the clock and look to dig in.The home crowd will be happy to boo and whistle the Gunners whenever they are in possession and that may add to the anxiety that has appeared to engulf Mikel Arteta’s men.Saturday’s 1-0 win over Newcastle ended a run of three games without a victory, while extending their run of failing to score more than once in a match to seven fixtures.Arsenal’s set-piece success means they should score, but Atleti’s prowess on the break will also create chances and a draw could prove to be a fair result.Last dance for Griezmann?Antoine Greizmann departs Atletico at the end of the season, with his move to MLS Outfit Orlando City already confirmed.The Frenchman is a club legend but only has a Europa League and a couple of Super Cup medals to show for his efforts, having lost in the Champions League final in 2016 and been at Barcelona when Atleti won the league in 2021.Despite Atletico’s inconsistency, Griezmann has had an excellent individual campaign, scoring two goals and providing five assists in his 13 Champions League appearances.After defeat in the Copa del Rey final earlier this month, this tournament is all that remains if he is to add to that Europa League medal.Intriguingly, he scored against the Gunners when the pair met at the Emirates in that tournament in 2018 and will relish his task on Wednesday.Koke a true card candidateMidfielder Koke is another Atleti icon who is out of contract in the summer and he has reminded everyone of his importance by enjoying something of a renaissance in 2025-26.Pablo Barrios’ injury means the 34-year-old is almost guaranteed to play and he will be in the thick of the action against Martin Zubimendi and Declan Rice.His eight fouls committed from 14 Champions League outings are relatively meagre, but his only booking was received in the first leg of the 3-2 aggregate victory against Barca in the quarter-finals. A one-club player, Koke will happily take a caution if it helps his team to get a result.GET UP TO £40 IN FREE BETS WHEN YOU BET ON THE FOOTBALL WITH talkSPORT BETOdds correct at time of publish and subject to change**18+ New customers only. Opt in and bet up to £40 (min. £20) via mobile or app on any football (odds 1/1+) within 7 days of registration. Get up to £40 in free bets on selected markets, which expire in 7 days. T&Cs apply. GambleAware.org | Please gamble responsiblyRemember to gamble responsiblyA responsible gambler is someone who:Establishes time and monetary limits before playingOnly gambles with money they can afford to loseNever chase their lossesDoesn’t gamble if they’re upset, angry or depressedGamCare – www.gamcare.org.ukGamble Aware – www.gambleaware.orgFor help with a gambling problem, call the National Gambling Helpline on 0808 8020 133 or go to www.gamstop.co.uk to be excluded from all UK-regulated gambling websites.Commercial content notice: Taking one of the bookmaker offers featured in this article may result in a payment to talkSPORT. 18+. T&Cs apply. gambleaware.org