Composed of five or more elements in nearly equal amounts, high-entropy alloys (HEAs) have emerged as promising catalysts due to their compositionally complex surfaces that can accelerate chemical reactions. Until now, scientists have not been able to precisely engineer these surface structures at the nanoscale, making it difficult to study how particle shape influences catalytic performance. Now, a study led by Northwestern University professors Chad A. Mirkin and Christopher M. Wolverton has solved that problem. The research is published in the Journal of the American Chemical Society.