Why Protagonist Therapeutics Stock Skyrocketed by Almost 30% Today

Wait 5 sec.

':"";if(a){var r=n.promos.showYahooLogo?"":"yns-no-logo";a=a.replace("{notifOnboardBtnLabel}",n.promos.notifOnboardBtnLabel).replace("{notifOnboardMsg}",n.promos.notifOnboardMsg).replace("{subscriptionTopic}",n.promos.subscriptionTopic).replace("{noLogoClass}",r).replace("{promoLogo}",n.promos.promoLogo)}var s=t.newCount>n.panel.maxCount?t.newCount:"",c=n.panel.notificationCenterPath,l=c?"":R,u=n.panel.headerMsg?"":" "+R,d=c?H:"",p=void 0;t.count?p=t.markup:p='{emptyPanelMsg}'.replace("{emptyPanelMsg}",n.panel.emptyPanelMsg);return e=e.replace("{notifMarkup}",p).replace("{promoMarkup}",a).replace("{hideClass}",l).replace("{notifCenterLink}",c).replace("{paddingClass}",d).replace("{headerMsg}",n.panel.headerMsg).replace("{hideHeaderClass}",u).replace(/{notificationCenterNavMsg}/g,n.panel.notificationCenterNavMsg).replace(/{newCount}/g,s)}},{key:"render",value:function(e,t){var n=this;if(n._panelNode){var o=void 0,i=n._panelNode,a=void 0,r=void 0;switch(e){case"expanded_panel":o='{promoMarkup}{notifMarkup}',r=n._store.getNotifications(),a=n._generatePanelMarkup(o,r),i.innerHTML=a;break;case"error_panel":a=(o='{errorMsg}').replace("{errorMsg}",n._config.panel.errorMsg),i.innerHTML=a}t&&t()}else t&&t(new Error("No panel parent"))}},{key:"createPanelParentNode",value:function(e){e&&(e.innerHTML='',this._panelNode=document.getElementById(P))}},{key:"updateBadgeNode",value:function(e){if(e){var t=this._store.getNotifications().newCount,n=this._config.badge.maxCount;if(t){var o=t>n?n+"+":t;e.innerHTML=o}else e.innerHTML=""}}},{key:"addStyles",value:function(e){if(e&&"undefined"!=typeof window){var t=document.getElementById(this._config.panel.styleTagId);t||((t=document.createElement("style")).type="text/css",t.id=this._config.panel.styleTagId,t.innerText=e,document.head.appendChild(t))}}}]),e}(),j=function(){function e(t,n,o){E(this,e);var i=this;i._store=n,i._view=o,i._config=t;var a=i._config.panel;i._panelParentNode=document.querySelector(a.parentSelector),i._badgeNode=i._config.badge.selector&&document.querySelector(i._config.badge.selector),i._indicatorNode=a.indicatorSelector&&document.querySelector(a.indicatorSelector)}return k(e,[{key:"createPanelParentNode",value:function(){this._view.createPanelParentNode(this._panelParentNode),this._notifPanelNode=document.getElementById(P)}},{key:"refreshPanelNode",value:function(e,t){var n=this;x(n._notifPanelNode,D),n._store.fetchNotifications(e,(function(e,o){var i=window.wafer&&window.wafer.base;i&&i.destroy(n._notifPanelNode),e?n._notifPanelNode.innerHTML||(n._view.render("error_panel"),x(n._notifPanelNode,D)):(n._view.render("expanded_panel"),n._view.updateBadgeNode(n._badgeNode),n._showBadge(),n._showIndicator(),n._view.addStyles(o.css)),N(n._notifPanelNode,D),i&&i.sync(n._notifPanelNode.parentNode),t&&t(e,o)}))}},{key:"resetBadge",value:function(){var e=this;e._store.resetNewCount(),e._view.updateBadgeNode(e._badgeNode),x(e._badgeNode,e._config.badge.hideClass)}},{key:"_showIndicator",value:function(){this._indicatorNode&&(this._store.getNotifications().newCount?x(this._indicatorNode,this._config.panel.indicatorClass):N(this._indicatorNode,this._config.panel.indicatorClass))}},{key:"_showBadge",value:function(){var e=this;e._store.getNotifications().newCount?N(e._badgeNode,e._config.badge.hideClass):x(e._badgeNode,e._config.badge.hideClass)}}]),e}(),Y={promos:{eligibleBodyClass:"display-push-promos",enableNotifOnboard:!0,bypassEligibleClassCheck:!1,notifOnboardBtnLabel:"Notify Me",notifOnboardMsg:"Get alerts for breaking news and top stories",promoLogo:"https://s.yimg.com/cv/apiv2/ae/news/circle_bell.png",showYahooLogo:!0,subscriptionTopic:"gondor_homerun_news"},badge:{hideClass:"",maxCount:5,selector:""},panel:{emptyPanelMsg:"You have no new notifications.",errorMsg:"",headerMsg:"Notifications",imageTag:"img:40x40|2|80",indicatorClass:"yns-indicator",indicatorSelector:null,maxCount:6,notificationCenterNavMsg:"View all {newCount} notifications",notificationCenterPath:"",notificationTypes:"",parentSelector:null,styleTagId:"notificationStyles",theme:"default"},service:{attemptCount:1,attemptDelay:2,url:null,resetUrl:null,isRMP:!1,responseType:"json",timeout:1500}},F={NotificationClient:function(){function e(t){E(this,e);var n=this;n.config=n._parseConfig(t),n._validateRequiredConfigs()&&(n._request=new S(n.config),n._store=new B(n.config,n._request),n._view=new U(n.config,n._store),n._panelController=new j(n.config,n._store,n._view),n._panelController.createPanelParentNode(),n._assignHelperMethods())}return k(e,[{key:"_parseConfig",value:function(e){var t={};for(var n in I(t,Y),t)if(t.hasOwnProperty(n)){var o=t[n],i=e[n];"object"===(void 0===o?"undefined":L(o))?I(o,i):t[n]=e[n]}return t}},{key:"_validateRequiredConfigs",value:function(){var e=this.config;return!(!e.panel.parentSelector||!e.service.url)}},{key:"_assignHelperMethods",value:function(){var e=this;e.helpers={refreshPanelNode:e._panelController.refreshPanelNode.bind(e._panelController),resetBadge:e._panelController.resetBadge.bind(e._panelController),resetIndicator:function(){N(e._panelController._indicatorNode,e.config.panel.indicatorClass)}}}}]),e}()},z="lnct",W=function(){function e(){var e,t;this.personalized=!1,this.ybarElem=document.getElementById("ybar"),this.partnerClasses=null===(t=null===(e=this.ybarElem)||void 0===e?void 0:e.className)||void 0===t?void 0:t.match(/ybar-variant-([a-z]*)/),this.client=new F.NotificationClient(this.getConfig())}return e.prototype.refreshPanel=function(){var e,t,n,o=this,i={lastUpdate:this.getTimeStamp()||this.setTimeStamp(),loadInHpViewer:!0,includePersonalized:this.personalized},a=(null===(e=window.YAHOO)||void 0===e?void 0:e.context)||(null===(t=window.Af)||void 0===t?void 0:t.context)||{};return a.region&&a.lang&&(i.lang=a.lang,i.region=a.region),(null===(n=this.partnerClasses)||void 0===n?void 0:n.length)&&(i.partner=this.partnerClasses[1]),new Promise((function(e,t){o.client.helpers.refreshPanelNode({matrixParams:i},(function(n,o){n&&(l("Notification refresh error:",n),t(n)),e(o)}))}))},e.prototype.resetBadge=function(){this.client.helpers.resetBadge(),this.setTimeStamp()},e.prototype.getConfig=function(){var e,t,n,o,i,a=document.getElementById("notification-container"),r=null===(e=null==a?void 0:a.dataset)||void 0===e?void 0:e.config;if(q&&!r)return q;var s={promos:{eligibleBodyClass:"display-push-promos",enableNotifOnboard:!0},badge:{selector:"#notif-badge",hideClass:"ybar-notification-hidden"},panel:{emptyPanelMsg:"You have no new notifications.",errorMsg:"Please check back later.",headerMsg:"Notifications",maxCount:5,parentSelector:"#ybarNotificationBody",notificationTypes:"breakingNews"},service:{url:"/tdv2_fp/api/resource/NotificationHistory.getHistory",isRMP:!1}},c={};if(r){"att"===(null===(t=this.partnerClasses)||void 0===t?void 0:t[1])&&(s.promos.showYahooLogo=!1);try{var u=JSON.parse(r);c=m({},u),this.personalized=1===u.personalize}catch(e){l("Notifications config parsing error",e)}a&&delete a.dataset.config}return q=this.mergeConfigs(s,c),(null===(n=this.partnerClasses)||void 0===n?void 0:n.length)&&"yahoo"!==(null===(o=this.partnerClasses)||void 0===o?void 0:o[1])&&(null===(i=q.promos)||void 0===i?void 0:i.subscriptionTopic)&&delete q.promos.subscriptionTopic,q},e.prototype.mergeConfigs=function(e,t){var n=m({},e);for(var o in e)n[o]=m(m({},e[o]),t[o]);return n},e.prototype.getTimeStamp=function(){var e;return null===(e=window.localStorage)||void 0===e?void 0:e.getItem(z)},e.prototype.setTimeStamp=function(){var e,t=""+Math.floor((new Date).getTime()/1e3);return null===(e=window.localStorage)||void 0===e||e.setItem(z,t),t},e}(),G=new W,K=function(){return G},J="",V=[],$=function(){},X=function(){window.removeEventListener("beforeunload",X),""!==J&&l("Rapid not found on page",new Error(J))},Z=null,Q=function(){return null===Z&&(Z=document.getElementById("ybar")),Z},ee=function(){var e=0,t=window.YAHOO;if(T)return T;if(t)if(t.i13n)if(t.i13n.__RAPID_INSTANCES__)if(t.i13n.__RAPID_INSTANCES__.length0)for(var n=0;n0){if(T.addModules(i,!1,o),V.length>0)for(e=0;e40959)&&(i19903)&&(i55215))return!1}return!0},ve={navBeaconFired:!1},ye=["ready","navigation"],he=function(){function e(e){var t=this;this.triggerEvent=s,this.addEventListener=c,this.logError=l,this.logPerformance=u,this.getConfig=d,this.getPerformanceMetrics=p,this.rapidRefresh=ne,this.state=m({},ve),this.modules=e,this.userEmail="",window.YBAR&&(ye.forEach((function(e){var n="on".concat(e),o=window.YBAR[n];o&&(t[n]=o)})),window.YBAR.wssid&&(this.wssid=window.YBAR.wssid),window.YBAR.appid&&(this.appid=window.YBAR.appid)),ye.forEach((function(e){var n="on".concat(e);c(e,(function(){for(var o,i=[],a=0;a0){if(o&&i){var n=t>99;o.classList.add("".concat(At)),i.classList.add("count-loaded"),o.textContent=n?"99+":t+"",n?o.classList.add("".concat(Ct)):t>=10&&o.classList.add("".concat(St))}e.onDestroy((function(){o&&(o.textContent="")}))}})).catch((function(){}))}(e,s)}));var Ut="_yb_1e46uhr",jt=function(e,t){var n;t.logoImages&&(n=t.logoImages).length>0&&Array.prototype.forEach.call(n,(function(e){e.onerror=function(){e.onerror=null,e.style.display="none"}})),t.wrapper&&(function(e,t){e&&(xe("#ybar-logo","#ybar-logo",t),t.onDestroy((function(){e.classList.remove("ybar-show-outline"),e.classList.remove("ybar-hide-outline")})))}(t.wrapper,e),function(e,t){t&&e.addElementListener(t,"click",(function(){e.triggerEvent("logo-click")}))}(e,t.wrapper))};ge("ybar-mod-logo",(function(e){var t={wrapper:document.getElementById("ybar-logo"),logoImages:document.querySelectorAll(".".concat(Ut))};jt(e,t)}));var Yt={"dropdown-open":"_yb_1qr55t8","merchant-is-selected":"_yb_hpfgev",overlay:"_yb_1t4opbo","selected-merchant-clear-button":"_yb_sdzekv","shops-buttons":"_yb_1gmhi8h","styled-select":"_yb_1fed2vs",tooltip:"_yb_156j5sr","tooltip--show":"_yb_t94u7s",tooltip__text:"_yb_149d3c6",tooltip__voice:"_yb_rkldcd",tooltip__web:"_yb_1bze76z",dark:"_yb_of9a42",darker:"_yb_1br2rz9",light:"_yb_p0373k","search-border-gradient":"_yb_109k2ga","search-border-gradient-hover":"_yb_vljmzl",midnight60:"_yb_1o792pg","search-input-uh3-hover":"_yb_15ox84z","search-input-uh3-focus-visible":"_yb_1e6541m","sa-btn-bar":"_yb_1axm66t","searchbox-icon-uh3":"_yb_1uef33k",empty:"_yb_owcm9n"},Ft=function(e,t){var n=Math.max(e,t),o=Math.min(e,t),i=Math.abs(n-o);return b([],h(new Array(i+1)),!1).map((function(e,t){return o+t}))},zt=function(e,t,n){var o=e.getConfig().bucketConfig,i=(void 0===o?{}:o).enable_search_ui,a=void 0!==i&&i;if(t.ybar){t.ybar.classList.add("ybar-searchbox-assist-fullscreen"),document.documentElement.classList.add("ybar-overlay"),document.body.classList.add("ybar-overlay-noscroll");te("ybar","websrch","",{elm:"expand",subsec:"searchbox",itc:"1"}),setTimeout((function(){t.searchInput instanceof HTMLInputElement&&(n&&(t.searchInput.value=n),t.searchInput.focus(),a&&window.YAHOO&&window.YAHOO.SA&&window.YAHOO.SA.apps&&window.YAHOO.SA.apps[0]&&window.YAHOO.SA.apps[0].view&&!window.YAHOO.SA.apps[0].view.shown&&window.YAHOO.SA.apps[0].view.show())}))}},Wt=function(e){var t;null===(t=e.ybar)||void 0===t||t.classList.remove("ybar-searchbox-assist-fullscreen"),document.documentElement.classList.remove("ybar-overlay"),document.body.classList.remove("ybar-overlay-noscroll"),e.searchInput instanceof HTMLInputElement&&(e.searchInput.value="",e.searchInput.blur())},Gt=function(e,t){var n=e.getConfig();"smartphone"===n.device&&("finance"===n.property&&"crunch"===n.ytheme&&e.addElementListener(t.searchInput,"click",(function(){var n,o;n="search_input_focus_click",null!==(o=re())&&(oe[n]||(oe[n]=o)),e.addElementListener(t.searchForm,"click",(function(){if(t.ybar){if(t.ybar.classList.contains("ybar-searchbox-assist-fullscreen"))return;t.ybar.classList.add("ybar-searchbox-assist-fullscreen"),t.ybar.classList.add("ybar-searchbox-assist-fadein")}if(!document.documentElement.classList.contains("ybar-overlay")){document.documentElement.classList.toggle("ybar-overlay"),document.body.classList.add("ybar-overlay-noscroll");te("ybar","websrch","",{elm:"expand",subsec:"searchbox",itc:"1"})}}))})),e.addElementListener(t.searchBoxPlaceholder,"click",(function(){zt(e,t)})),e.addElementListener(t.searchBoxPlaceholder,"keydown",(function(n){var o=n,i=o.keyCode,a=o.key,r=Ft(65,90),s=b(b([],h(Ft(58,57)),!1),h(Ft(96,105)),!1),c=b(b([],h(r),!1),h(s),!1).includes(i);(32===i||13===i||c)&&(n.preventDefault(),n.stopPropagation(),zt(e,t,c?a:""))})),t.searchBoxBackButton&&(e.addElementListener(t.searchBoxBackButton,"click",(function(e){e.stopPropagation(),window.YAHOO&&window.YAHOO.SA&&window.YAHOO.SA.apps&&window.YAHOO.SA.apps[0]&&(window.YAHOO.SA.apps[0].view.resetQuery(),window.YAHOO.SA.apps[0].view.hide()),Wt(t);te("ybar","back-close-srch","",{elm:"btn",subsec:"searchbox",itc:"1"})})),e.addElementListener(t.searchInput,"keyup",(function(e){e.stopPropagation();27===e.keyCode&&(e.stopPropagation(),Wt(t))}))),e.addEventListener("viewerClosed",(function(){Wt(t)})),e.onDestroy((function(){Wt(t)})))},Kt=function(){function e(e,t,n){t&&(this.ybar=e,this.elem=t,this.options=n,this.show=this.show.bind(this),this.hide=this.hide.bind(this),this.addEventListeners())}return Object.defineProperty(e.prototype,"tooltip",{get:function(){var e=this;return this.tooltipMarkup||(this.tooltipMarkup=this.createTooltip(),(this.options.tooltipParentElm||this.elem).appendChild(this.tooltipMarkup),this.ybar.onDestroy((function(){var t,n;null===(n=null===(t=e.tooltipMarkup)||void 0===t?void 0:t.parentNode)||void 0===n||n.removeChild(e.tooltipMarkup)}))),this.tooltipMarkup},enumerable:!1,configurable:!0}),e.prototype.show=function(){this.tooltip.classList.add(this.options.showClass)},e.prototype.hide=function(){this.tooltip.classList.remove(this.options.showClass)},e.prototype.addEventListeners=function(){this.ybar.addElementListener(this.elem,"mouseenter",this.show),this.ybar.addElementListener(this.elem,"focus",this.show),this.ybar.addElementListener(this.elem,"mouseleave",this.hide),this.ybar.addElementListener(this.elem,"blur",this.hide)},e.prototype.createTooltip=function(){var e=document.createElement("div");e.className=this.options.containerClass||"";var t=document.createElement("p");return t.textContent=this.options.label,t.className=this.options.textClass||"",e.appendChild(t),e},e}(),Jt={containerClass:Yt.tooltip,textClass:Yt.tooltip__text,showClass:Yt["tooltip--show"]};ge("ybar-mod-searchbox",(function(e){var t,n=e.getConfig(),o={ybar:document.getElementById("ybar"),searchInput:document.getElementById("ybar-sbq"),buttonBar:document.querySelector(".".concat(Yt["sa-btn-bar"])),searchForm:document.getElementById("ybar-sf"),searchBoxIcon:document.querySelector(".".concat(Yt["searchbox-icon-uh3"])),searchBoxPlaceholder:document.getElementById("ybar-smartphone-searchbox-placeholder"),searchBoxBackButton:document.getElementById("ybar-search-back-btn"),shopsButtonsWrap:document.querySelector(".".concat(Yt["shops-buttons"])),categorySelect:document.getElementById("shops-category-select"),selectedMerchantInput:document.getElementById("selected-merchant-input"),selectedMerchantClearButton:document.querySelector(".".concat(Yt["selected-merchant-clear-button"])),submitSearchBtn:document.getElementById("ybar-search"),clearSearchBtn:document.getElementById("ybar-sbq-x"),searchGradientBorder:document.querySelector(".".concat(Yt["search-border-gradient"]))};if(function(e,t){var n,o,i,a=e.getConfig();if(t.ybar&&"desktop"===a.device&&(null===(n=a.bucketConfig)||void 0===n?void 0:n.highlight_searchassist)&&(null===(o=a.bucketConfig)||void 0===o?void 0:o.overlay_class)){t.ybar.setAttribute("data-ovrly-bkt",a.bucketConfig.overlay_class),null===(i=t.searchForm)||void 0===i||i.classList.add(Yt[a.bucketConfig.overlay_class]);var r=document.createElement("div");r.classList.add(Yt.overlay,Yt[a.bucketConfig.overlay_class]),document.body.appendChild(r),e.onDestroy((function(){document.body.removeChild(r)})),e.addElementListener(t.searchForm,"focusout",(function(e){if(t.searchForm&&t.searchInput){var n=e.relatedTarget;n&&!t.searchForm.contains(n)&&window.YAHOO.SA&&window.YAHOO.SA.apps&&window.YAHOO.SA.apps[0]&&window.YAHOO.SA.apps[0].view.shown&&window.YAHOO.SA.apps[0].view.hide()}}))}}(e,o),Gt(e,o),o.searchGradientBorder){var i=!1;o.searchInput.addEventListener("keydown",(function(e){var t=e.code,n=e.key,a=t.startsWith("Key"),r=t.startsWith("Digit"),s=/^[!@#$%^&*()_+\-=[\]{};':"\\|,./?`~]$/.test(n);(a||r||s)&&!i&&(o.searchGradientBorder.classList.add("".concat(Yt["search-border-gradient-hover"])),i=!0)})),e.addElementListener(o.searchForm,"mouseover",(function(){i||o.searchGradientBorder.classList.add("".concat(Yt["search-border-gradient-hover"]))})),e.addElementListener(o.searchForm,"mouseout",(function(){i||o.searchGradientBorder.classList.remove("".concat(Yt["search-border-gradient-hover"]))})),e.addElementListener(o.searchInput,"click",(function(){i=!0})),e.addElementListener(o.searchInput,"blur",(function(){o.searchGradientBorder.classList.remove("".concat(Yt["search-border-gradient-hover"]))}))}o.searchForm&&(e.addElementListener(o.searchBoxIcon,"mouseover",(function(){o.searchForm.classList.add("".concat(Yt["search-input-uh3-hover"]))})),e.addElementListener(o.searchBoxIcon,"mouseout",(function(){o.searchForm.classList.remove("".concat(Yt["search-input-uh3-hover"]))})),e.addElementListener(o.buttonBar,"mouseover",(function(){o.searchForm.classList.add("".concat(Yt["search-input-uh3-hover"]))})),e.addElementListener(o.buttonBar,"mouseout",(function(){o.searchForm.classList.remove("".concat(Yt["search-input-uh3-hover"]))})),e.addElementListener(o.searchInput,"keyup",(function(e){"Tab"===e.key&&o.searchForm.classList.add("".concat(Yt["search-input-uh3-focus-visible"])),o.searchInput.classList.toggle("".concat(Yt.empty),""===o.searchInput.value)})),e.addElementListener(o.searchInput,"keydown",(function(){o.searchForm.classList.remove("".concat(Yt["search-input-uh3-focus-visible"]))})),e.addElementListener(o.searchInput,"focusout",(function(){o.searchForm.classList.remove("".concat(Yt["search-input-uh3-focus-visible"]))})),e.addElementListener(o.submitSearchBtn,"click",(function(e){""===o.searchInput.value.trim()&&e.preventDefault()})),e.addElementListener(o.clearSearchBtn,"click",(function(){o.searchInput.classList.add("".concat(Yt.empty))}))),o.submitSearchBtn&&"crunch"===n.ytheme&&new Kt(e,o.submitSearchBtn,m(m({},Jt),{label:null!==(t=n.i18n.root.SEARCH_TOOLTIP_WEB)&&void 0!==t?t:"Search the web",containerClass:"".concat(Yt.tooltip," ").concat(Yt.tooltip__web),tooltipParentElm:o.clearSearchBtn.parentElement}))}));var Vt="_yb_tdk4ba",$t="_yb_hkd17a",Xt="_yb_rtzclf",Zt="_yb_tdbhj6",Qt="_yb_de52ef",en="_yb_9hwrey",tn="_yb_slc8ta",nn="_yb_bf0svp",on="_yb_hjic9z";ge("ybar-mod-adaptivenav",(function(e){var t=document.querySelector("#ybar-l1-more-menu ul"),n={moreDropDown:document.querySelector(".".concat(Vt)),moreBtn:document.querySelector(".".concat($t)),wrap:document.querySelector(".".concat(Zt)),moreSectionTitle:document.querySelectorAll(".".concat(Qt)),editionsCtaBtn:document.querySelector(".".concat(en)),editionsMenu:document.querySelector(".".concat(tn)),closeBtn:document.querySelector(".".concat(nn)),moreMenuDropDownHeight:t?"".concat(t.offsetHeight+48,"px"):"0"};new Ke(e,{adaptiveNavBtn:n.moreBtn,containerElm:n.moreDropDown,innerContainerElm:n.editionsMenu,isAdaptiveNav:!0});var o=!1,i=function(t,n){var o=t.moreDropDown,i=t.moreBtn,a=t.wrap,r={sec:"ybar",slk:"More",elm:"expand",pkgt:"top",subsec:"navrail",itc:"1"};o&&i&&a&&o.classList.contains("".concat(Vt))&&(o.style.height=t.moreMenuDropDownHeight,o.classList.remove("".concat(Vt)),a.classList.add("".concat(Xt)),i.setAttribute("aria-expanded","true"),r.elm="expand",e.triggerEvent("adapnav:more:show",{event:n}),te("ybar",r.slk,"",r))},a=function(e,t){void 0===t&&(t=!1);var n=e.moreDropDown,i=e.moreBtn,a=e.wrap,r={sec:"ybar",slk:"More",elm:"close",pkgt:"top",subsec:"navrail",itc:"1"};n&&i&&a&&(n.classList.contains("".concat(Vt))||(n.classList.add("".concat(Vt)),n.style.height="0",a.classList.remove("".concat(Xt)),i.setAttribute("aria-expanded","false"),o||t||te("ybar",r.slk,"",r)))},r=function(e,t){void 0===t&&(t=!1);var n=e.editionsMenu,o={sec:"ybar",slk:"More",elm:"close",pkgt:"top",subsec:"navrail",itc:"1"};null==n||n.close(),null==n||n.classList.remove("".concat(on)),t||te("ybar",o.slk,"",o)},s=function(){var e;window.innerWidth a"),o=document.querySelector("#ybar-navigation-item-mail > a > span");null!==t&&null!==n&&(new Rt).fetchCount().then((function(t){o&&t>0&&(o.textContent="("+(t>99?"99+":t)+")",e.onDestroy((function(){o.textContent=""})))})).catch((function(){}))},Rn=!1,Hn=-1,Un=function(e,t,n){var o,i,a,r=-1,s=0;if(e.ybarNav&&e.navList){var c=window.getComputedStyle(e.ybarNav),l=parseInt(c.width,10)-parseInt(c.paddingLeft,10)-parseInt(c.paddingRight,10),u=61,d=e.navigationPlacement();if(d)u+=d.getBoundingClientRect().width;if(Sn)u+=Sn.getBoundingClientRect().width;for(var p=window.getComputedStyle(e.navList),f=parseInt(p.gap,10)||0,m=0;mg&&(m!==e.navItems.length-1||s+h>g||e.moreMenuDropdown&&e.moreMenuDropdown.hasChildNodes()&&Hn10?e.moreMenuDropdown.classList.add(e.longListClass):null!==e.moreMenuDropdown&&e.moreMenuDropdown.classList.remove(e.longListClass))}},jn=function(e,t){var n,o=function(e,n){var o;e.classList.contains(t.moreMenuNavItemClass)&&(null===(o=t.moreMenuMainFocusItem)||void 0===o||o.setAttribute("aria-expanded",n))},i=function(){t.isTablet&&(document.body.classList.remove("ybar-nav-open"),document.body.removeEventListener("touchend",u))},a=function(n){var i=n.delegateTarget;i&&i.classList.contains(t.dropdownWrapperClass)&&(i.classList.contains(t.dropdownOpenClass)||(e.triggerEvent("nav:dropdown:show",{event:n}),t.isTablet&&(document.body.classList.add("ybar-nav-open"),document.body.addEventListener("touchend",u)),i.classList.add(t.dropdownOpenClass),o(i,"true")))},r=function(e){var n=e.delegateTarget;if(null==n?void 0:n.classList.contains(t.navigationDropdownListClass)){var a=n.parentElement;a&&!a.contains(e.relatedTarget)&&a.classList.contains(t.dropdownWrapperClass)&&(i(),a.classList.remove(t.dropdownOpenClass),o(a,"false"))}else if(null==n?void 0:n.classList.contains(t.dropdownOpenClass)){if(t.isTablet&&e instanceof FocusEvent)return;var r=e.target;Sn&&(!Sn||Sn.contains(r)&&"focusout"!==e.type)||(i(),n.classList.remove(t.dropdownOpenClass),o(n,"false"))}},s=ze(".".concat(t.dropdownWrapperClass),"focusin",a),c=ze(".".concat(t.dropdownWrapperClass,", .").concat(t.navigationDropdownListClass),"focusout",r),l=document.getElementById("ybar-navigation"),u=function(e){var n=null==e?void 0:e.target;t.isTablet&&e&&e.target&&e.target instanceof HTMLElement&&(e.target.classList.contains(t.dropdownOpenClass)||e.target.closest(".".concat(t.dropdownOpenClass)))||document.body.classList.contains("ybar-nav-open")&&!["svg","path"].includes(n.tagName)&&(null==l||l.querySelectorAll(".".concat(t.dropdownOpenClass)).forEach((function(e){e.classList.remove(t.dropdownOpenClass)})),i())};e.addEventListener("nav:closeOverflowMenu",(function(){u()}));var d=ze(".".concat(t.dropdownWrapperClass),"touchstart",(function(e){if(t.isTablet){var n=e.delegateTarget;n&&n.classList.contains(t.dropdownOpenClass)?r(e):(u(e),a(e))}})),p=null===(n=t.ybarNav)||void 0===n?void 0:n.querySelectorAll(".".concat(qn));null==p||p.forEach((function(t){var n=t.parentNode;n&&null!==document.querySelector(".ybar-ytheme-crunch")&&e.addElementListener(n,"mouseenter",(function(t){e.triggerEvent("nav:dropdown:show",{event:t})}))})),e.onDestroy((function(){var e;d.destroy(),s.destroy(),c.destroy(),b([],h(null===(e=t.ybarNav)||void 0===e?void 0:e.querySelectorAll(".".concat(t.dropdownOpenClass))),!1).forEach((function(e){e.classList.remove(t.dropdownOpenClass);var n=document.activeElement;(function(e,t){var n=!1;if(!e||!t)return n;if("function"==typeof e.contains)n=e.contains(t);else for(var o=t;o;){if(o===e){n=!0;break}o=o.parentElement}return n})(t.ybarNav,n)&&setTimeout((function(){null==n||n.blur()}),1)}))}))},Yn=function(e,t,n,o){for(var i=t||window.location.pathname,a=n||window.location.hostname,r=(o||{}).setParentFocus,s=void 0!==r&&r,c=b([],h(e.topLevelNavLinks),!1),l=null,u=null,d=0;d li"),dropdownClass:t.dropdownWrapperClass,enableMoreMenu:i,moreMenuNavElm:t.moreMenuMainFocusItem,isUserAccountNavigation:!1});!function(e,t){var n,o;b([],h(null===(n=t.ybarNav)||void 0===n?void 0:n.querySelectorAll(".".concat(t.dropdownOpenClass))),!1).forEach((function(e){return e.classList.remove(t.dropdownOpenClass)}));var i=e.getConfig();Sn=(null===(o=i.bucketConfig)||void 0===o?void 0:o.enable_mid_nav_placement)?document.getElementById("ybar-mid-nav-placement"):void 0,"news"===i.property?Cn=-12:(Cn="finance"!==i.property&&"sports"!==i.property&&t.shiftMoreMenuEnabled?-24:-16,"zh-Hant-HK"!==i.locale&&"zh-Hant-TW"!==i.locale||(Cn=-20));var a=t.isTablet?"touchstart":"mouseover",r=ze(".".concat(t.dropdownWrapperClass,", .").concat(t.navigationDropdownListClass),a,(function(n){if(window||document){var o=window.innerWidth||document.documentElement.clientWidth,a=n.delegateTarget;if(a&&-1!=a.className.indexOf(t.dropdownWrapperClass)&&(a=a.querySelector(".".concat(t.navigationDropdownListClass))),a){a.style.removeProperty("left");var r=a.getBoundingClientRect(),s=Math.trunc(r.right),c=parseInt(window.getComputedStyle(a).marginLeft,10)+o-s;if(s>o)return"sports"!==i.property?void(a.style.marginLeft=c+"px"):void(a.style.right="0px");if(parseInt(a.style.marginLeft)0?a.style.removeProperty("margin-left"):a.style.marginLeft=c+"px":(a.style.removeProperty("margin-left"),a.style.marginLeft=Cn+"px"),t.isTablet){var l=a.previousElementSibling;if(Sn&&Sn.contains(a));else if(l){var u=l.getBoundingClientRect(),d=Math.trunc(u.left);a.style.left=d+"px"}}}}else{var p=new Error("Dropdown could not be initialized");e.logError("Error:",p)}}));e.onDestroy((function(){r.destroy()}))}(e,t),Pn(e),e.addElementListener(document,"DOMContentLoaded",(function(){Pn(e)})),jn(e,t);var r=e.getConfig().bucketConfig,s=void 0===r?{}:r,c=s.enableDynamicNavfocus,l=void 0!==c&&c,u=s.enableFuzzyMatching;if(l&&(Rn=void 0!==u&&u,Yn(t)),e.addEventListener("nav:setFocus",(function(e){var n=e.detail,o=void 0===n?{}:n,i=o.hostname,a=void 0===i?window.location.hostname:i,r=o.pathname,s=void 0===r?window.location.pathname:r,c=o.options;Yn(t,s,a,void 0===c?{}:c)})),i){var d=document.createElement("style");d.title="ybar_nav_interim",document.head.appendChild(d);var p=ze("#ybar-nav-more-menu ul a","click",(function(t){e.triggerEvent("navigation",{event:t})}));e.addEventListener("nav:resize",(function(){Un(t,d,a)})),Un(t,d,a);var f=e.getConfig();if("complete"===document.readyState)Fn(e,t,d,a);else{var m="load";("news"===f.property&&("zh-Hant-TW"===f.locale||"zh-Hant-HK"===f.locale)||"finance"===f.property&&"zh-Hant-TW"===f.locale)&&(m="DOMContentLoaded"),e.addElementListener(window,m,(function(){Fn(e,t,d,a)}))}e.addElementListener(window,"resize",(function(){Un(t,d,a)})),e.onDestroy((function(){var e=d.parentNode;null==e||e.removeChild(d),p.destroy()}))}Gn(e,t)},Wn=function(e,t){var n=["zh-Hant-TW","zh-Hant-HK"].includes(e.getConfig().locale);return t.isFuji2&&n},Gn=function(e,t){if(t.isNavHidden){var n=!1;e.addElementListener(document,"DOMContentLoaded",(function(n){t.isNavHidden()&&e.triggerEvent("l2:hide",{event:n})})),e.addElementListener(window,"resize",(function(o){!n&&t.isNavHidden()&&e.triggerEvent("l2:hide",{event:o}),n=t.isNavHidden()}))}},Kn="#ybar-nav-more-menu";ge("ybar-mod-navigation",(function(e){var t,n=e.getConfig(),o={dropdownWrapperClass:xn,isFuji2:null!==document.querySelector(".ybar-ytheme-fuji2")||null!==document.querySelector(".ybar-ytheme-crunch"),isTablet:null!==document.querySelector(".tablet")||"tablet"===n.device||matchMedia("(hover: none)").matches,longListClass:Nn,moreMenuDropdown:document.querySelector("".concat(Kn," ul")),moreMenuNavItem:document.querySelector(Kn),moreMenuNavLinksSelector:"".concat(Kn," ul a"),moreMenuMainFocusItem:document.querySelector("".concat(Kn," > button")),moreMenuNavItemClass:Dn,navigationDropdownItemClass:In,navigationDropdownListClass:qn,navItems:document.querySelectorAll("ul.".concat(Bn," li.").concat(On)),topLevelNavLinks:document.querySelectorAll("li.".concat(On," > a")),navLinks:document.querySelectorAll(".ybar-mod-navigation a"),navList:document.querySelector(".ybar-mod-navigation ul"),shiftMoreMenuEnabled:document.querySelector(".ybar-shift-more-menu"),ybarNav:document.getElementById("ybar-navigation"),ybarNavigationItemClass:On,dropdownOpenClass:An,hasNavPlacement:document.getElementById("ybar-nav-placement"),marginOffset:function(e){var t=window.getComputedStyle(e),o=parseInt(t.marginLeft,10)+parseInt(t.marginRight,10);return"sports"===n.property?parseInt(t.marginRight):"finance"===n.property&&"crunch"===n.ytheme?(o-=1.8)>5?o:5:"crunch"===n.ytheme?o:0},navigationPlacement:function(){return t||(t=document.getElementById("ybar-nav-placement")),t},isNavHidden:function(){var e=!1;return"finance"===n.property&&"crunch"===n.ytheme&&document.documentElement.clientWidth=5||n.initialized?clearInterval(a):(void 0!==n.isNotificationsSupported()&&n.init(),i++)}),100)}return e.prototype.show=function(e){var t;this.initialized&&(this.historyEnabled&&!e||(document.body.classList.add(eo),null===(t=this.a11yMenu)||void 0===t||t.setAttribute("aria-expanded","true"),this.lastSeen=(new Date).getTime()))},e.prototype.hide=function(){var e;this.initialized&&(this.historyEnabled&&document.body.classList.remove(to),document.body.classList.remove(eo),null===(e=this.a11yMenu)||void 0===e||e.setAttribute("aria-expanded","false"))},Object.defineProperty(e.prototype,"lastSeen",{get:function(){return this.state.lastSeen},set:function(e){this.state.lastSeen=e,this.setLocalStorage()},enumerable:!1,configurable:!0}),Object.defineProperty(e.prototype,"manuallyClosed",{get:function(){return this.state.manuallyClosed},set:function(e){this.state.manuallyClosed=!!e,this.setLocalStorage()},enumerable:!1,configurable:!0}),e.prototype.init=function(){this.isNotificationsSupported()&&this.isNotificationPermissionDefault()&&(this.historyEnabled||document.body.classList.add(to),this.addEventListeners(),this.initialized=!0,this.hasSeenTooltipIn(this.manuallyClosed?6048e5:Qn)||(document.body.classList.add(to),this.show(!0)))},e.prototype.addEventListeners=function(){var e=this;this.ybar.addElementListener(this.container.getElementsByClassName(no)[0],"click",(function(){e.hide(),e.manuallyClosed=!0}))},e.prototype.isNotificationsSupported=function(){var e;return null===(e=null===window||void 0===window?void 0:window.subscriptionHelperInstance)||void 0===e?void 0:e.checkIsSupportedBrowser()},e.prototype.isNotificationPermissionDefault=function(){var e;return"default"===(null===(e=window.Notification)||void 0===e?void 0:e.permission)},e.prototype.hasSeenTooltipIn=function(e){if(!this.lastSeen)return!1;var t=new Date(this.lastSeen),n=new Date;return t.getTime()+e>n.getTime()},e.prototype.setLocalStorage=function(){var e;null===(e=window.localStorage)||void 0===e||e.setItem(Zn,JSON.stringify(this.state))},e.prototype.getLocalStorage=function(){var e,t,n=null===(e=window.localStorage)||void 0===e?void 0:e.getItem(Zn);if(null===n)return null;try{return JSON.parse(n)}catch(e){return null===(t=window.localStorage)||void 0===t||t.removeItem(Zn),null}},e}(),ao=-1,ro={0:0,1:1,9:9,99:99,150:150},so=function(e,t){var n,o=t.isUH3,i=t.notifMenu,a=t.notifMenuOpener,r=t.notifDropdown,s=t.notifBadge,c=t.notifContainer,l=t.notifLabel;t.tooltipContainer&&(n=new io(e,t.tooltipContainer));var u=K(),d=function(){i&&(i.checked=!1),null==r||r.classList.remove("ybarMenuOpen")},p=function(){var t;e.triggerEvent("close-all-menus"),!!document.querySelector(".display-push-promos .".concat(Jn))||(u.resetBadge(),s&&(o?null===(t=s.parentElement)||void 0===t||t.classList.remove(Vn):s.style.display="none"))},f=function(e){var t,n;0===ao&&(null===(t=null==e?void 0:e.css)||void 0===t?void 0:t.length)&&e.css.length>0&&(ao++,function(e){for(var t=function(e){var t=document.createElement("link");t.rel="stylesheet",t.type="text/css",t.href=e,document.getElementsByTagName("head")[0].appendChild(t)},n=0;n0&&s)if(o){var a,r=(a=e.newCount)>99;s.textContent=r?"99+":a+"",null===(n=s.parentElement)||void 0===n||n.classList.add(Vn)}else s.style.display="block"},m=function(){u.refreshPanel().then(f).then(ne).catch((function(){}))};if(e.addEventListener("close-all-menus",(function(){Ce(c)||d()})),c){m();var v=setInterval((function(){m()}),3e5);e.onDestroy((function(){clearInterval(v)})),o?l&&l.addEventListener("mouseenter",(function(){p(),null==n||n.show()})):c.addEventListener("mouseenter",(function(){p(),null==n||n.show()})),c.addEventListener("mouseleave",(function(){d(),null==n||n.hide()}))}e.addElementListener(i,"click",(function(){te("ybar","notification","",{elm:"btn",elmt:"block"===(null==s?void 0:s.style.display)?"newalert":"",subsec:"notification",itc:"1"})})),a&&Ae(e,a,"ybar","notification",{elm:"expand",subsec:"notifications",itc:"2"}),e.addElementListener(r,"focusin",(function(){i&&(i.checked=!0),null==r||r.classList.add("ybarMenuOpen")})),e.addElementListener(r,"focusout",d),e.addElementListener(t.tooltipContainer,"focusin",(function(){null==n||n.show()})),e.addElementListener(t.tooltipContainer,"focusout",(function(){null==n||n.hide()}));var y=e.getConfig().device,h=document.getElementById("ybar");h&&h.classList.contains("ybar-ytheme-crunch")&&(ao=0);var b=new RegExp("[?&]notifications=1(&|#|$)");"desktop"===y&&i&&b.test(window.location.search)&&(i.checked=!0)};ge("ybar-mod-notification",(function(e){var t={isUH3:"crunch"===e.getConfig().ytheme,notifContainer:document.getElementById("notification-container"),notifBadge:document.getElementById("notif-badge"),notifMenu:document.getElementById("ybarNotificationMenu"),notifMenuOpener:document.querySelector("#ybarNotificationMenu + label"),notifDropdown:document.getElementById("notifDropdownContainer"),tooltipContainer:document.querySelector(".".concat($n)),notifLabel:document.querySelector(".".concat(Xn))};t.notifDropdown&&so(e,t)}))}()}};]]>Eric Volkman, The Motley FoolSat, October 11, 2025 at 1:07 AM GMT+2 3 min readA large, veteran enterprise in the healthcare sector is apparently interested in acquiring it.According to a media report, discussions on a deal are at an early stage.10 stocks we like better than Protagonist Therapeutics ›Clinical-stage biotech Protagonist Therapeutics (NASDAQ: PTGX) was all the rage on the stock market Friday. The company's share price closed a dizzying 29.8% higher on the day, thanks to intense takeover speculation. That leap was particularly notable considering it was quite a downbeat day for stocks overall, with the S&P 500 (SNPINDEX: ^GSPC) sliding by almost 3%.That speculation was fired that morning by The Wall Street Journal, which reported healthcare giant Johnson & Johnson was in discussions to acquire Protagonist. Although it gleaned this from unidentified "people familiar with the matter," the financial newspaper had few details to report about the apparent negotiations.Image source: Getty Images.Protagonist is well known to Johnson & Johnson, as the two companies collaborate on the development of a drug that combats immune disorders such as ulcerative colitis. If and when the medication is developed successfully and comes to market, Johnson & Johnson will hold its exclusive commercialization rights.If the report is accurate, the would-be acquirer wouldn't be snapping up Protagonist at a bargain. Thanks largely to positive results in clinical trials for several of its pipeline drugs, the biotech's share price had risen in excess of 70% year to date -- and that was before Friday's monster pop.Neither Protagonist nor Johnson & Johnson has yet commented on the WSJ report, which is par for the course in early stages of such events. I should stress that this has to be considered speculation at this point, although I would advise investors of either company (or both) to keep a sharp eye on how the apparent deal might shape up.Before you buy stock in Protagonist Therapeutics, consider this:The Motley Fool Stock Advisor analyst team just identified what they believe are the 10 best stocks for investors to buy now… and Protagonist Therapeutics wasn’t one of them. The 10 stocks that made the cut could produce monster returns in the coming years.Consider when Netflix made this list on December 17, 2004... if you invested $1,000 at the time of our recommendation, you’d have $663,905!* Or when Nvidia made this list on April 15, 2005... if you invested $1,000 at the time of our recommendation, you’d have $1,180,428!*Terms and Privacy PolicyPrivacy & Cookie SettingsMore InfoS&P 5006,552.51 -182.60 (-2.71%)Dow 3045,479.60 -878.82 (-1.90%)Nasdaq22,204.43 -820.20 (-3.56%)Russell 20002,394.60 -74.25 (-3.01%)VIX21.66 +5.23 (+31.83%)Gold4,000.40 +27.80 (+0.70%)PortfolioSign in to access your portfolioSign inTop gainersPTGX Protagonist Therapeutics, Inc. 87.00 +19.96 (+29.77%)APLD Applied Digital Corporation 33.99 +4.70 (+16.05%)NAMS NewAmsterdam Pharma Company N.V. 37.05 +4.05 (+12.26%)FRMI Fermi Inc. 29.08 +2.31 (+8.63%)MP MP Materials Corp. 78.34 +6.05 (+8.37%)Top losersVG Venture Global, Inc. 9.45 -3.13 (-24.88%)DGNX Diginex Limited 24.93 -6.46 (-20.58%)CORT Corcept Therapeutics Incorporated 73.96 -14.40 (-16.30%)WRD WeRide Inc. 10.17 -1.80 (-15.04%)AMBA Ambarella, Inc. 72.88 -11.40 (-13.53%)Most activeNVDA NVIDIA Corporation 183.16 -9.34 (-4.85%)BBAI BigBear.ai Holdings, Inc. 7.22 -0.27 (-3.60%)BITF Bitfarms Ltd. 4.2000 +0.0300 (+0.72%)INTC Intel Corporation 36.37 -1.43 (-3.78%)PLUG Plug Power Inc. 3.4200 -0.3600 (-9.52%)Earnings eventsMy earnings eventsEarnings eventsTrending tickersBTC-USD Bitcoin USD 111,786.69 -78.68 (-0.07%)PPL PPL Corporation 37.23 +0.29 (+0.79%)NVX NOVONIX Limited 2.9400 +0.7750 (+35.80%)MMM 3M Company 148.75 -4.13 (-2.70%)OPAI.PVT OpenAI 723.12 0.00 (0.00%)Top economic events