Z Gerontol Geriatr. 2025 Jul 29. doi: 10.1007/s00391-025-02472-y. Online ahead of print.ABSTRACTCoronary artery disease (CAD) is a continuum between chronic (CCS) and acute coronary syndrome (ACS). It is the leading cause of death in older people. In addition to the prognostic relevance, angina pectoris, dyspnea or fatigue lead to impaired quality of life. The basic diagnostics include anamnesis, physical examination, 12-lead electrocardiography (ECG), laboratory diagnostics and transthoracic echocardiography. Functional investigations, such as stress magnetic resonance imaging (MRI), stress echocardiography, myocardial scintigraphy and direct imaging techniques, such as coronary computed tomography (CT) and invasive coronary angiography are available. The treatment depends on the severity of the symptoms, the patient's wishes and the risk of the procedure. Regardless of age, the basic treatment is strict optimization of risk factors, antithrombotic antianginal therapy. Revascularization is reserved for patients with refractory symptoms or a high-risk constellation.PMID:40728725 | DOI:10.1007/s00391-025-02472-y