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RegExp("[?&]notifications=1(&|#|$)");"desktop"===y&&i&&b.test(window.location.search)&&(i.checked=!0)};be("ybar-mod-notification",(function(e){var t={isUH3:"crunch"===e.getConfig().ytheme,notifContainer:document.getElementById("notification-container"),notifBadge:document.getElementById("notif-badge"),notifMenu:document.getElementById("ybarNotificationMenu"),notifMenuOpener:document.querySelector("#ybarNotificationMenu + label"),notifDropdown:document.getElementById("notifDropdownContainer"),tooltipContainer:document.querySelector(".".concat(Vn)),notifLabel:document.querySelector(".".concat($n))};t.notifDropdown&&ro(e,t)}))}()}};]]>Prosper Junior Bakiny, The Motley FoolMon, Jul 21, 2025, 2:15 PM 5 min readPfizer and Novo Nordisk have underperformed the market over the past year.But both should remain major players in important areas within the pharma industry.Investors could see the two drugmakers' shares beat the market over the next decade.10 stocks we like better than Pfizer ›Pharmaceutical giants Pfizer (NYSE: PFE) and Novo Nordisk (NYSE: NVO) have lagged the market over the past year, although Pfizer's poor performance dates back much further. Though these companies have encountered challenges, there are good reasons to be bullish on their long-term prospects.Pfizer could become an even bigger player in the oncology market (the largest therapeutic area in the industry by sales) over the next decade, while Novo Nordisk will be a major player in diabetes and the fast-growing weight management space. Both could produce excellent results along the way. Here's the rundown.Image source: Getty Images.Pfizer's financial results haven't been great in recent years. To make matters worse, the company will face important patent cliffs by the end of the decade. One of them will be for Eliquis, an anticoagulant that is still one of its best-selling medicines. However, Pfizer has prepared for that eventuality.The company made several acquisitions and licensing deals that significantly boosted its pipeline, especially in oncology. Pfizer spent $43 billion to acquire Seagen, a smaller cancer specialist whose lineup and pipeline were impressive for a company of its size. With the financial and strategic backing of the larger company, it should yield even more key approvals in the field in the coming years.Pfizer also recently made an up-front payment of $1.25 billion to China-based 3SBio for the rights to SSGJ-707, an investigational bispecific antibody, a portion of the oncology market that's gaining traction these days. 3SBio will be eligible for commercial and regulatory milestone payments of up to $4.8 billion, not including royalties.These moves should eventually pay off for Pfizer and strengthen its position in oncology. The drugmaker plans to have eight blockbuster cancer medicines on the market by 2030, up from its current five, while doubling its reach from the current 1 million patients it serves. Of course, Pfizer isn't just a cancer play. The company's extensive pipeline should enable it to launch products in other areas and ultimately get back on track.While its shares have been lagging the market significantly, that could change in the next decade as financial results rebound thanks to its innovative efforts. Pfizer's shares look especially attractive when considering its valuation. Its forward price-to-earnings (P/E) ratio is 8.7, much lower than the healthcare sector's 15.8. From their current levels, Pfizer's shares could go on to generate excellent returns through 2035.Terms and Privacy PolicyPrivacy & Cookie SettingsMore InfoS&P Futures6,356.75 +10.00 (+0.16%)Dow Futures44,798.00 +87.00 (+0.19%)Nasdaq Futures23,239.75 +13.50 (+0.06%)Russell 2000 Futures2,269.90 +9.20 (+0.41%)VIX16.50 -0.15 (-0.90%)Gold3,442.90 -0.80 (-0.02%)PortfolioSign in to access your portfolioSign inTop gainersMEDP Medpace Holdings, Inc. 477.73 +168.85 (+54.67%)IQV IQVIA Holdings Inc. 187.38 +28.42 (+17.88%)DHI D.R. 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