Q&APublished: 21 July 2025Melina Casadio1 Nature Structural & Molecular Biology (2025)Cite this articleSubjectsChromatinDNA replicationFrancesca Mattiroli leads a research group at the Hubrecht Institute in Utrecht in the Netherlands, delving into the dynamics of chromatin during DNA synthesis. Here we ask her about her research ethos, experience and interests.This is a preview of subscription content, access via your institutionAccess optionsAccess Nature and 54 other Nature Portfolio journalsGet Nature+, our best-value online-access subscription27,99 € / 30 dayscancel any timeLearn moreSubscribe to this journalReceive 12 print issues and online access209,00 € per yearonly 17,42 € per issueLearn moreBuy this articlePurchase on SpringerLinkInstant access to full article PDFBuy nowPrices may be subject to local taxes which are calculated during checkoutAuthor informationAuthors and AffiliationsNature Structural & Molecular Biology https://www.nature.com/nsmb/Melina CasadioAuthorsMelina CasadioView author publicationsSearch author on:PubMed Google ScholarCorresponding authorCorrespondence to Melina Casadio.Rights and permissionsReprints and permissionsAbout this article