1 Under-$10 Stock Set to Surge as Much as 963% in 2026

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In most sectors, that kind of upside is almost unheard of. Some biotech stocks, however, are an exception. When encouraging clinical data and regulatory milestones align, a single breakthrough can rapidly reprice a biotech stock. That is precisely why Wall Street expects this under-$10 biotech company to skyrocket by as much as 404% in 2026. Let’s find out why.Arcturus Therapeutics (ARCT) is a biotechnology company that develops messenger RNA (mRNA)-based medicines and vaccines. Instead of treating symptoms, Arcturus seeks to address the root cause of the problem by helping the body make the right proteins on its own. Valued at $194.3 million, ARCT stock dipped 64% last year, compared to the S&P 500 Index ($SPX) gain of 16%. However, the stock is up 10% so far this year.Can Chevron Stock Hit $205 in 2026?The Saturday Spread: Reading the Market’s Signals to Jump Ahead of the Crowd (HPE, SNOW, CRWD)As Meta Delays New Ray-Ban Display Glasses, Should You Buy, Sell, or Hold META Stock?Our exclusive Barchart Brief newsletter is your FREE midday guide to what's moving stocks, sectors, and investor sentiment - delivered right when you need the info most. Subscribe today!The company has already developed the world’s first approved self-amplifying mRNA Covid-19 vaccine, KOSTAIVE. It continues to collaborate with global partners to develop mRNA-based vaccines for Covid-19 variants and pandemic influenza. It is also working on developing mRNA therapies for cystic fibrosis (CF) and ornithine transcarbamylase (OTC) deficiency, a serious inherited disorder.www.barchart.comArcturus is emerging as one of the most closely watched under-$10 biotech stocks heading into 2026, driven by encouraging clinical data, a clearer pipeline roadmap, and aggressive cost controls that extend its financial runway. Momentum is building around ARCT-032, Arcturus’ inhaled mRNA therapeutic candidate for cystic fibrosis. Interim Phase 2 data released in October indicated that daily 10 mg treatment for 28 days in six Class I CF adults was generally safe and well tolerated. Importantly, protocol-specified high-resolution CT scan analysis employing FDA-cleared AI technology revealed reductions in mucus burden in four of the six patients.Building on these early indications, Arcturus intends to launch a 12-week safety and preliminary efficacy study in up to 20 CF patients in the first half of 2026. In addition, the company is enrolling a third cohort to study a higher 15 mg daily dose over 28 days, which will help refine the program's dose-response profile. These next trial steps are essential since positive findings will considerably bolster the ARCT-032 investment thesis. Beyond CF, Arcturus is developing ARCT-810 for OTC deficiency, a rare genetic metabolic condition. The company aims to collaborate with regulatory agencies on pivotal trial designs for both pediatric and adult populations in the first half of 2026, ensuring that this second key product remains on schedule. Arcturus’ platform continues to be validated through its vaccine programs. In Japan, partner Meiji Seika Pharma issued an enhanced two-dose vial of KOSTAIVE targeting the JN.1 variant XEC in August 2025, following regulatory approval. Additional Phase 3 and Phase 1 trials on Covid-19 and pandemic influenza candidates indicated significant immune responses, excellent safety profiles, and support for continued development of the company's STARR self-amplifying mRNA technology. These data highlight the versatility of Arcturus’ mRNA platform across both therapeutics and vaccines.Terms and Privacy PolicyPrivacy & Cookie SettingsMore InfoS&P Futures6,966.50 -38.50 (-0.55%)Dow Futures49,468.00 -258.00 (-0.52%)Nasdaq Futures25,727.00 -211.25 (-0.81%)Russell 2000 Futures2,622.20 -14.70 (-0.56%)VIX14.49 -0.41 (-2.75%)Gold4,581.50 +80.60 (+1.79%)Trending tickersBTC-USD Bitcoin USD 91,694.41 +1,080.90 (+1.19%)IREN IREN Limited 46.03 +0.35 (+0.77%)NQ=F Nasdaq 100 Mar 26 25,727.00 -211.25 (-0.81%)GC=F Gold Feb 26 4,581.50 +80.60 (+1.79%)ETH-USD Ethereum USD 3,147.70 +54.80 (+1.77%)PortfolioSign in to access your portfolioSign inTop gainersNBY NovaBay Pharmaceuticals, Inc. 19.16 +12.41 (+183.85%)CGON CG Oncology, Inc. 54.20 +12.27 (+29.26%)BE Bloom Energy Corporation 134.07 +30.20 (+29.07%)KRMN Karman Holdings Inc. 106.22 +22.23 (+26.47%)WRBY Warby Parker Inc. 28.30 +5.05 (+21.72%)Top losersAYI Acuity Inc. 325.55 -51.14 (-13.58%)SGHC Super Group (SGHC) Limited 10.50 -1.41 (-11.84%)HPP Hudson Pacific Properties, Inc. 9.72 -1.26 (-11.48%)CVI CVR Energy, Inc. 22.97 -2.82 (-10.93%)MOD Modine Manufacturing Company 125.14 -15.30 (-10.89%)Most activeINTC Intel Corporation 45.55 +4.44 (+10.80%)OPEN Opendoor Technologies Inc. 7.28 +0.83 (+12.88%)NVDA NVIDIA Corporation 184.83 -0.21 (-0.11%)ONDS Ondas Holdings Inc. 13.69 -0.32 (-2.28%)PLUG Plug Power Inc. 2.1900 -0.1300 (-5.60%)Top economic eventsEarnings eventsMy earnings eventsEarnings events