England were dealt a massive pre-match blow against Italy when Tom Curry hobbled off during the warm-ups.The flanker was due to start in their penultimate Six Nations clash on Saturday evening.England staff had to help Curry as he made his way off the pitchGettyHowever, Curry was seen limping off the pitch at the Stadio Olimpico with the help of medical staff.It is not yet clear as to what injury the 27-year-old sustained.Sam Underhill was the man to replace Curry in the starting line-up as England look for a response to back-to-back defeats.Strong start, poor responseEngland opened their Six Nations campaign with a thumping 48-7 win over Wales.Henry Arundell scored a hat-trick of tries as the Red Roses won a 12th consecutive match.However, a trip to Murrayfield ended in a 31-20 defeat to Scotland, who won the Calcutta Cup for the fifth time in six years. England were then thumped 42-21 by Ireland as their Six Nations hopes came crashing down at Twickenham.Steve Borthwick’s side have won all 26 of their matches against Italy prior to this weekend’s match.It’s the only fixture in the tournament in which one team holds a 100 per cent record against their opponent.Another victory over Italy would help make up for what has been a tough run-out in the 2026 Six Nations.View Tweet: https://twitter.com/hashtag/GuinnessM6N?src=hash&ref_src=twsrc%5Etfw