Aminoglycosides are antibiotics effective against a wide range of bacteria including Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus. Until now however, their mode of entry into bacteria has remained unknown. Scientists at the Institut Pasteur, working with teams from Inserm, the CNRS and Université Paris Cité, have recently demonstrated that aminoglycosides enter bacteria by using sugar transporters.