New weight loss pill delivers ‘significant’ results in study | The IndependentNotifications can be managed in browser preferences.Jump to contentIndependentNext articleIndependent Bulletin homepageDownload ourSocial PartnerWe are 8 logo (opens in a new tab)AllNewsSportCultureLifestyleRebecca WhittakerWednesday 17 September 2025 06:56 BSTThe one surprising impact of weight loss jab OzempicA new once-a-day pill, Orforglipron, has demonstrated “significant” reductions in body weight, potentially offering a more accessible and cheaper alternative to existing injectable weight-loss medications.A study published in the New England Journal of Medicine revealed that almost one in five participants (18.4 per cent) taking the highest dose of Orforglipron lost 20 per cent or more of their body weight over 72 weeks.The research, which involved 3,127 participants from various countries, also showed that those on the highest 36mg dose experienced an average weight loss of 11.2 per cent.Experts anticipate that the tablet form will simplify obesity treatment and enhance convenience, thereby broadening access to effective weight-loss medications for more individuals.In addition to weight loss, patients using Orforglipron saw improvements in blood pressure, waist circumference, and cholesterol levels, with common side effects being mild to moderate gastrointestinal issues.In fullVital breakthrough as once-a-day pill can help people lose ‘significant’ weightThank you for registeringPlease refresh the page or navigate to another page on the site to be automatically logged inPlease refresh your browser to be logged in