Tottenham could be without as many as ten first-team players ahead of their crucial Champions League tie against AS Monaco.Tottenham Hotspur are currently camped outside the automatic qualification places in the Champions League league phase table. Two matches have been played, but given how competitive the competition is, Tottenham need to start putting points on the board to avoid slipping further behind.Last time out in Europe, Spurs were held to a 2-2 draw by Bodo/Glimt, as they had to dig deep and come from behind in the Arctic Circle.Tottenham will now be hoping to record their second win on the international stage when they travel to France to face AS Monaco, a side that drew last time out with Manchester City.Credit: @thefrederikkejensen / InstagramTottenham boss Thomas Frank battling major injury troublesThomas Frank, however, goes into the cup tie with several injury concerns to contend with following the latest setbacks among his defensive ranks. Cristian Romero is nursing a minor abductor problem, while Destiny Udogie missed the clash against Aston Villa due to irritation in his knee.That leaves Frank short at the back, with Radu Dragusin, Ben Davies, and Takai also sidelined and unavailable for selection. The situation could hardly have come at a worse time, as Spurs look to build momentum both domestically and in Europe. Spurs’ Champions League squad limitations add to Frank’s headacheFrank was unable to register a full 25-man squad for the Champions League, leaving him naturally short of options for rotation. Mathys Tel missed out on Frank’s Champions League squad, while Dejan Kulusevski, Yves Bissouma, and James Maddison were also among those left out, and given their ongoing injury problems, Frank would have still been left short.The Dane will likely stick with the same back line he deployed against Aston Villa, with Pedro Porro, Kevin Danso, Micky van de Ven, and Djed Spence expected to form the rearguard once again. But with options at the back few, Tottenham would be hoping that their defenders do not pick up any more injuries, as games are set to come thick and fast in the coming weeks.READ MORE: Former Premier League star hints Heung-min Son may have made a big Tottenham mistakeThe post Tottenham set to be without 10 first-team players for Champions League clash vs Monaco appeared first on Spurs Web.