Barcelona resume UEFA Champions League duties on Tuesday as they host Olympiacos in one of the early kickoffs.The Catalans battled to a 2-1 derby win on Saturday over Girona thanks to Ronald Araujo's 93rd-minute goal. The result was something of a relief to Hansi Flick after back-to-back losses to Paris Saint-Germain and Sevilla prior to the October international break.Barca won their Champions League opener at Newcastle United before that defeat to the holders, so the visit of the Greek Super League's dominant force offers them a chance to move back towards the higher positions in the league-phase standings. Only the top eight sides at the end of this initial stage are guaranteed a place in the knockout rounds.With El Clasico looming on October 26, Flick must ensure he manages the minutes of his available key players carefully. Barca's injury list is already quite long, and any further losses before next Sunday could make the task against Real Madrid particularly daunting.MORE: El Clasico: History of rivalry and all-time head-to-head between Barcelona and Real MadridBarcelona vs. Olympiacos lineups: Predicted starting XI, team news, injury latestFlick will need to strike a balance in his selection given they had only two full days of rest after the win over Girona and face the small matter of El Clasico at the weekend.Wojciech Szczesny will likely keep his place in goal as Joan Garcia is not expected back until November. Ronald Araujo could come into the back four after his match-winning cameo against Girona.Pedri may be given a rest, which would mean Fermin Lopez starting as the No. 10 and Marc Casado partnering Frenkie de Jong in midfield.With Ferran Torres to be given additional time to recover from a muscle issue so he is ready for Real Madrid, Flick suggested he could hand a start to Roony Bardghji after his impressive performance off the bench against Girona. That could see Marcus Rashford pushed up into the No. 9 role.Lamine Yamal should start but, given his persistent groin trouble, he is unlikely to play the full 90 minutes.Barcelona predicted starting XI (4-2-3-1, right to left): Szczesny (GK) — Kounde, Araujo, Cubarsi, Balde — De Jong, Casado — Lamine Yamal, Lopez, Bardghji — RashfordInjured: J. Garcia (knee), Gavi (knee), Lewandowski (hamstring), Olmo (calf), Raphinha (hamstring), Ter Stegen (back), Torres (hamstring)Suspended: NoneOlympiacos are without the experienced full-back Rodinei, but they otherwise have a strong travelling squad, having come through the weekend win over largely unscathed.Brazilian winger Gabriel Strefezza has missed his side's past two league games with a niggling injury and is a doubt to feature in Catalonia.Guilian Biancone could return at centre-back, while Gelson Martins may get the nod over Yusuf Yazici after being rested at the weekend.Olympiacos predicted starting XI (4-2-3-1, right to left): Tzolakis (GK) — Costinha, Biancone, Retsos, Ortega — Hezze, Scipioni — Gelson Martins, Chiquinho, Podence — El KaabiInjured: Rodinei (calf), Strefezza (knock, doubt)Suspended: NoneBarcelona vs. Olympiacos match detailsDate: Tuesday, October 21, 2025Kickoff time: 6:45 p.m. local / 12:45 p.m. ET / 9:45 a.m. PT / 3:45 a.m. AEDT (Oct. 22)Location: Estadi Olimpic Lluis Companys, Barcelona (Spain)Competition: UEFA Champions League league phase: Matchday 3Referee: Urs Schnyder (SUI)VAR: Fedayi San (SUI)Latest Barcelona newsBarcelona could battle Real Madrid for England aceFrenkie de Jong speaks out on Miami controversy: 'I don't like it'Could Lewandowski follow the Luis Suarez path out of Barcelona?