/u/astonedishape on "Free" toxic trees... you bring the soil and shovels!

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It’s a very reliable source. He links the 14 peer reviewed studies mentioned under sources. Google it yourself. Do you know how to read epidemiological studies? Brannan RG, Peters T, Talcott ST. Phytochemical analysis of ten varieties of pawpaw (Asimina triloba [l. ] dunal) fruit pulp. Food Chem. 2015;168:656-661. Levine RA, Richards KM, Tran K, Luo R, Thomas AL, Smith RE. Determination of neurotoxic acetogenins in pawpaw (Asimina triloba) fruit by lc-hrms. J Agric Food Chem. 2015;63(4):1053-1056. Majrashi TA, Zulfiqar F, Chittiboyina AG, Ali Z, Khan IA. Isoquinoline alkaloids from Asimina triloba. Nat Prod Res. 2019;33(19):2823-2829. McLaughlin JL. Paw paw and cancer: annonaceous acetogenins from discovery to commercial products. J Nat Prod. 2008;71(7):1311-1321. Adainoo B. North American pawpaw (Asimina triloba L.) fruit: A critical review of bioactive compounds and their bioactivities. Trends Food Sci. 2024;149:104530. Potts LF, Luzzio FA, Smith SC, Hetman M, Champy P, Litvan I. Annonacin in Asimina triloba fruit: implication for neurotoxicity. Neurotoxicology. 2012;33(1):53-58. Park HK, Ilango SD, Litvan I. Environmental risk factors for progressive supranuclear palsy. J Mov Disord. 2021;14(2):103-113. Lannuzel A, Ruberg M, Michel PP. Atypical parkinsonism in the Caribbean island of Guadeloupe: etiological role of the mitochondrial complex I inhibitor annonacin. Mov Disord. 2008;23(15):2122-2128. Tran K, Ryan S, McDonald M, Thomas AL, Maia JGS, Smith RE. Annonacin and squamocin contents of pawpaw (Asimina triloba) and marolo (Annona crassiflora) fruits and atemoya (A. squamosa × A. cherimola) seeds. Biol Trace Elem Res. 2021;199(6):2320-2329. Cleret de Langavant L, Roze E, Petit A, et al. Annonaceae consumption worsens disease severity and cognitive deficits in degenerative parkinsonism. Mov Disord. 2022;37(12):2355-2366. Höllerhage M, Rösler TW, Berjas M, et al. Neurotoxicity of dietary supplements from annonaceae species. Int J Toxicol. 2015;34(6):543-550. Lannuzel A, Höglinger GU, Champy P, Michel PP, Hirsch EC, Ruberg M. Is atypical parkinsonism in the Caribbean caused by the consumption of Annonacae? J Neural Transm Suppl. 2006;(70):153-157. Pomper KW, Lowe JD, Crabtree SB, Keller W. Identification of annonaceous acetogenins in the ripe fruit of the North American pawpaw ( Asimina triloba ). J Agric Food Chem. 2009;57(18):8339-8343. Kaas B, Hillis AE, Pantelyat A. Progressive supranuclear palsy and pawpaw. Neurol Clin Pract. 2020;10(2):e17-e18.