Accurately measuring small shifts in biological markers, like proteins and neurotransmitters, or harmful chemicals in the water supply, can identify critical problems before they have a chance to impact patients or the environment. While some existing sensors can monitor the microscopic matter behind these issues, they often have limitations. A primary example is a device known as a field-effect transistor—a tiny component that controls the flow of electrical current in a system—that struggles to remain stable when exposed to liquid.