Borussia Dortmund have made a bright start to the season under Niko Kovac, a former Bayern Munich manager who is hoping to challenge his former club’s dominance of the Bundesliga this season.Can Dortmund collect another three points on Saturday, or will Mainz halt their momentum by coming out on top at the Mewa Arena?Borussia Dortmund to win – 21/20 with BetfredBorussia Dortmund to score first – 8/11 with MidniteSerhou Guirassy to score any time – 20/23 with ToteMainz vs Borussia Dortmund oddsFind the latest Mainz vs Borussia Dortmund betting odds here. All odds are provided by our recommended football bookmakers and are subject to change. Stay in-play between matches with bet365’s live casino! Mainz vs Borussia Dortmund predictionsHaving let a 4-2 lead slip against Juventus in second-half stoppage time last week, Borussia Dortmund needed to bounce with a win a few days later.That is exactly what they did, as Karim Adeyemi’s strike in the 20th minute brought BVB a 1-0 victory over Wolfsburg in the Bundesliga.Niko Kovac bemoaned his team’s defensive frailties against Juventus, so he must have been pleased to see Dortmund allow Wolfsburg zero shots on target.It was a deserved victory for the home side at Signal Iduna Park, and one which kept Dortmund within touching distance of Bayern Munich at the summit of the standings.Dortmund will aim to stay in that position for as long as possible. Bayern are clear favourites to end the campaign in first place, but Dortmund must believe they can push them all the way. Without that confidence, it will be tough for them to stick with the reigning champions.Dortmund should remind themselves that Bayern are not unassailable. Bayer Leverkusen won the title in 2023/24 and Stuttgart bumped the Bavarians down to third. A year earlier, Dortmund would have finished top had they not fluffed their lines (against Mainz, incidentally) on the final weekend.After that runners-up finish in 2022/23, Dortmund finished fifth and fourth in the next two seasons. With Kovac at the helm, it feels like they are ready to be competitive right at the top of the division again.Kovac took the reins at Signal Iduna Park in early February. In the 14 rounds of Bundesliga fixtures held since then, Dortmund have collected 28 points and Bayern have amassed 31. During Kovac’s tenure, BVB have been able to keep pace with Vincent Kompany’s charges.“I’m delighted that we won, that it was a clean sheet… we were fresh, energetic, and we gave pretty much nothing away,” Kovac said after the 1-0 triumph over Wolfsburg. “We deservedly won the match. We would, of course, have liked to win by a greater margin against a good, structured Wolfsburg team. The lads are continuing to improve, even if there are setbacks from time to time. But we are consistently taking steps forward.”Next up for Dortmund is this trip to Mainz, who have won one, drawn one and lost two of their first four matches.Mainz vs Borussia Dortmund betting tips. 18+ GambleAware.org – Please play responsibly.Mainz vs Borussia Dortmund betting tipsBorussia Dortmund travel to Mainz for their last Bundesliga match in September. Dortmund can collect victoryBorussia Dortmund won three out of their last four away games in the Bundesliga last term, a sequence of results which helped them squeeze into the top four.Their last domestic outing on the road saw BVB beat Heidenheim 2-0, although on the opening weekend they could only manage a 3-3 draw with St Pauli on their travels.If they want to compete with Bayern at the top of the table, Dortmund will not be able to rely solely on their home form.In other words, this is exactly the sort of match that Kovac’s men need to win if they want to be genuine title contenders.Mainz will look to make life difficult for Dortmund, but we fancy the latter to find a way through. Tip Borussia Dortmund to win at 21/20 with Betfred Dortmund to establish leadKovac will want to see his team hit the ground running on Saturday afternoon as they aim to add another three points to their tally.That should not be too difficult. Mainz have conceded the first goal in three of their four Bundesliga encounters up to now.Borussia Dortmund, for their part, have broken the deadlock in each of their six encounters in all competitions. BVB have tended to get out of the blocks quickly and that is likely to be the case when they face Mainz this weekend. Pick Borussia Dortmund to score first at 8/11 with Midnite Guirassy is main goal threatBorussia Dortmund have grown accustomed to selling their best players down the years, and Serhou Guirassy could be the next cab off the rank.The Guinea international enjoyed a terrific debut season at Signal Iduna Park, scoring 38 goals in 50 appearances in all competitions. He has made a fast start in 2025/26 too, making the net bulge five times across five domestic games. Four of those strikes have come in the Bundesliga, which means Guirassy has been outscored only by Harry Kane.Guirassy will be a threat against Mainz and we like his chances of getting his name on the scoresheet once more. Select Serhou Guirassy to score any time at 20/23 with Tote Mainz vs Borussia Dortmund predicted lineupsMainz expected lineup: Zentner; Da Costa, Bell, Hanche-Olsen; Widmer, Sano, Amiri, Mwene; Nebel, Nordin; Sieb.Borussia Dortmund expected lineup: Kobel; Anton, Schlotterbeck, Bensebaini; Ryerson, Sabitzer, Nmecha, Svensson; Adeyemi, Guirassy, Beier. Where to watch Mainz vs Borussia DortmundLocation: Mewa Arena, Mainz, Germany.Date and time: Saturday 27th September, 2pm.How to watch: Not being shown live in the UK.More Bundesliga predictionsWe have plenty more Bundesliga predictions and picks – find our latest betting tips from expert punters in our match preview overview.About the authorGreg LeaGreg Lea is a freelance football writer from London. He predominantly covers the Premier League and has had work published by the Guardian, FourFourTwo, ESPN and others.Follow Greg on X: @GregLeaFootballCommercial content notice: Taking one of the bookmaker offers featured in this article may result in a payment to talkSPORT. 18+. T&Cs apply. 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