Arsenal have lost out on another trophy after a shock 2-1 defeat to Southampton in the FA Cup quarter-finals.Shea Charles came off the bench to score the decisive goal with only five minutes to play at St Mary’s on Saturday night.Charles has sent Southampton into the FA Cup semi-finalsGettyArsenal looked to be heading for extra time when Viktor Gyokeres levelled after Ross Stewart opened the scoring for Southampton.But the Gunners, who lost to Manchester City in the Carabao Cup final less than two weeks ago, are now out of the FA Cup.It’s a significant moment in the season run-in, and comes just weeks after Arsenal were eyeing up a historic quadruple.They remain top of the Premier League and will play in the quarter-finals of the Champions League.However, the pressure will really begin to kick in when they navigate the final weeks of the campaign.“Southampton have dumped out the Premier League leaders,” said Alex Crook on talkSPORT. “The treble dream is over.”Former Gunner Perry Groves added: “Southampton thoroughly deserved it, both goals they scored were top quality.”“(Taylor) Harwood-Bellis was perfect, every Southampton player to a man did their job to perfection,” he also said.Arsenal have lost out on two pieces of silverware in two weeksGettyMore to follow…