Heron Therapeutics, Inc. Q4 2025 Earnings Call Summary

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n=e.getConfig();"smartphone"===n.device&&("finance"===n.property&&"crunch"===n.ytheme&&e.addElementListener(t.searchInput,"click",(function(){var n,o;n="search_input_focus_click",null!==(o=re())&&(oe[n]||(oe[n]=o)),e.addElementListener(t.searchForm,"click",(function(){if(t.ybar){if(t.ybar.classList.contains("ybar-searchbox-assist-fullscreen"))return;t.ybar.classList.add("ybar-searchbox-assist-fullscreen"),t.ybar.classList.add("ybar-searchbox-assist-fadein")}if(!document.documentElement.classList.contains("ybar-overlay")){document.documentElement.classList.toggle("ybar-overlay"),document.body.classList.add("ybar-overlay-noscroll");te("ybar","websrch","",{elm:"expand",subsec:"searchbox",itc:"1"})}}))})),e.addElementListener(t.searchBoxPlaceholder,"click",(function(){zt(e,t)})),e.addElementListener(t.searchBoxPlaceholder,"keydown",(function(n){var 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Q4 2025 Earnings Call Summary - MobyThe company successfully completed a financing round that eliminated a long-standing capital structure overhang, allowing management to focus entirely on commercial execution.Acute Care performance reached a strategic inflection point in Q4 2025, with ZYNRELEF and APONVIE delivering 48% and 97% year-over-year revenue growth, respectively.Operational improvements such as the CrossLink IGNITE distributor incentive program and the introduction of the vial access needle (VAN) significantly reduced hospital workflow friction.The implementation of permanent J-Codes for ZYNRELEF and APONVIE has improved reimbursement clarity, facilitating broader adoption across hospitals and ambulatory surgery centers.Oncology performance remained a stable revenue base, with CINVANTI showing resilience against competitive pressures while the company continues the planned wind-down of SUSTOL.Management is pivoting to a high-growth strategy by expanding sales capacity in priority geographies that exhibit favorable market access and established distributor relationships.Full year 2026 guidance projects net product sales between $173 million and $183 million, with adjusted EBITDA expected to remain positive between $10 million and $20 million.The company plans to increase commercial investments starting mid-2026, which may temporarily moderate EBITDA growth to prioritize long-term revenue acceleration and free cash flow in 2027.ZYNRELEF's prefilled syringe (PFS) presentation is undergoing 12 months of stability testing, with a targeted FDA approval and launch window in mid- to late 2027.APONVIE adoption is expected to accelerate in the second half of 2026 as its inclusion in the Fifth Consensus Guidelines for PONV management begins to influence hospital P&T committee cycles.The NOPAIN Act is anticipated to serve as a significant tailwind as provider awareness of separate reimbursement for non-opioid treatments increases throughout 2026.The Oncology franchise is undergoing a structural shift as SUSTOL is phased out through 2026, leading to a projected modest decline in total oncology revenue.CINVANTI faces ongoing competitive pricing dynamics in the clinic setting, though management expects to offset this through volume growth in the hospital segment.The transition to the prefilled syringe (PFS) will require careful inventory management of existing vial presentations to ensure a seamless market switch in 2027.Ongoing patent litigation regarding CINVANTI remains a factor, though management expressed confidence following the conclusion of trial briefing.Terms and Privacy PolicyPrivacy & Cookie SettingsMore InfoS&P 5006,878.88 -29.98 (-0.43%)Dow 3048,977.92 -521.28 (-1.05%)Nasdaq22,668.21 -210.17 (-0.92%)Russell 20002,632.36 -44.93 (-1.68%)VIX19.86 +1.23 (+6.60%)Gold5,296.40 +102.20 (+1.97%)Trending tickersBTC-USD Bitcoin USD 65,832.06 -1,429.70 (-2.13%)ANTH.PVT Anthropic 259.14 0.00 (0.00%)WFC Wells Fargo & Company 81.45 -4.85 (-5.62%)BX Blackstone Inc. 113.37 -4.58 (-3.88%)NBIS Nebius Group N.V. 91.19 -13.69 (-13.05%)PortfolioSign in to access your portfolioSign inTop gainersAAOI Applied Optoelectronics, Inc. 84.23 +30.54 (+56.88%)BWIN The Baldwin Insurance Group, Inc. 23.23 +4.74 (+25.64%)FIGS FIGS, Inc. 15.45 +2.98 (+23.90%)DELL Dell Technologies Inc. 148.08 +26.63 (+21.93%)PSKY Paramount Skydance Corporation 13.51 +2.33 (+20.84%)Top losersRUN Sunrun Inc. 13.25 -7.17 (-35.11%)FIGR Figure Technology Solutions, Inc. 25.28 -8.76 (-25.73%)CRWV CoreWeave, Inc. 79.56 -18.07 (-18.51%)ACA Arcosa, Inc. 107.48 -20.02 (-15.70%)TPC Tutor Perini Corporation 75.37 -14.01 (-15.67%)Most activeNVDA NVIDIA Corporation 177.19 -7.70 (-4.16%)NFLX Netflix, Inc. 96.24 +11.63 (+13.75%)SOFI SoFi Technologies, Inc. 17.76 -1.34 (-7.02%)PLUG Plug Power Inc. 1.7900 -0.1200 (-6.28%)NU Nu Holdings Ltd. 14.98 -0.08 (-0.53%)Top economic eventsEarnings eventsMy earnings eventsEarnings events